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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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A Convenient Synthesis of Quinolines via Ionic Liquid-Catalysed Friedlander Annulation
- Source: Letters in Organic Chemistry, Volume 5, Issue 1, Jan 2008, p. 47 - 50
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- 01 Jan 2008
Abstract
A convenient and green protocol for the synthesis of quinolines by Friedlander annulation using an acidic ionic liquid, ethylammonium nitrate, as both a catalyst and a reaction medium is reported. The reactions were performed at 45°C with moderate to excellent yields. The recovered ionic liquid could be reused for several cycles without any loss of activity.
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