Full text loading...
- ISSN: 1570-1786
- E-ISSN: 1875-6255
-
A Facile Synthesis of Lipo-Chitopentaose Nodulation Factor
- Source: Letters in Organic Chemistry, Volume 4, Issue 8, Dec 2007, p. 588 - 589
-
- 01 Dec 2007
Abstract
We prepared the penta-N-acetyl-chitopentaose 2 by using recombinant Escherichia coli (E. coli) strains harboring the nodC gene (encoding chitooligosaccharide synthase) from Azorhizobium caulinodans. The deacetylase NodB removed the N-acetyl moiety from the nonreducing terminus of 2 to give tetra-N-acetyl-chitopentaose 3. N-Acylation of 3 with stearyl chloride was performed in DMF containing water and provided the corresponding lipo-chitopentaose nodulation factor 4.
© Bentham Science Publishers