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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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One-Pot Regioselective Green Synthesis of Novel Quinolines Using a Neat Reaction Technology
- Source: Letters in Organic Chemistry, Volume 4, Issue 7, Oct 2007, p. 519 - 523
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- 01 Oct 2007
Abstract
A convenient eco-friendly procedure has been developed for the synthesis of novel quinoline derivatives by a simple one-pot reaction of substituted anilines with β-ketoesters under microwave irradiation without any solvent. A comparative study of reaction on solid support versus neat reaction is done. Neat reaction technology gives better yield in shorter reaction times and also cuts down the usage of solvent.
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