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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Novel Naproxen Derivatives: Lewis Acid/Transition-metal Free Synthesis via C-C Bond Forming Reaction
- Source: Letters in Organic Chemistry, Volume 4, Issue 4, Jun 2007, p. 292 - 295
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- 01 Jun 2007
Abstract
Naproxen or 2-(6-methoxy naphthalen-2-yl)propionic acid participated in trifluoroacetic anhydride/ phosphoric acid mediated C-C bond forming reaction in a regioselective fashion when treated with a variety of arene or heteroarene under a solvent-free condition affording novel 1-aryl/heteroaryl substituted 2-(6-methoxy naphthalen-2-yl)propan-1-ones in good yields.
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