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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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A Facile Regioselective Synthesis of Tetracyclic Sulphur Heterocycles by Tandem Thio-Claisen Rearrangement (SUPPORTING DATA)
- Source: Letters in Organic Chemistry, Volume 4, Issue 2, Mar 2007, p. 120 - 122
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- 01 Mar 2007
Abstract
Thio-Claisen rearrangement of symmetrically substituted 1,4-but-2-ynes (3a,b and 4) exhibit tandem cyclization and afforded compounds 5a,b and 6 in good yields. These sulphides 3a,b and 4 were in turn prepared from commercially available thiophene. The key step in this transformation is tandem [3,3] sigmatropic rearrangement.
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