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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Direct Synthesis of Weinreb Amides from Carboxylic Acids Using Triphosgene
- Source: Letters in Organic Chemistry, Volume 4, Issue 1, Jan 2007, p. 20 - 22
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- 01 Jan 2007
Abstract
Weinreb amides were conveniently prepared in high yields by reaction of carboxylic acids with N,Odimethylhydroxylamine hydrochloride at room temperature using triphosgene as an acid activator in the presence of triethylamine.
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