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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Aza-Michael Addition of Amines to Activated Alkenes Catalyzed by Silica Supported Perchloric Acid Under a Solvent-Free Condition
- Source: Letters in Organic Chemistry, Volume 4, Issue 1, Jan 2007, p. 54 - 59
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- 01 Jan 2007
Abstract
An efficient aza-Michael addition of amines to a series of α,β-unsaturated ketones, carboxylic esters, nitriles and chalcones has been carried out using perchloric acid supported over silica gel (HClO4-SiO2) at room temperature in high yields under solvent-free reaction conditions.
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