An Efficient and Selective End-Modification of High-Molecular Weight Poly(Ethylene Glycol)s

Pietro Campaner; Gian Maria Bonora; Sara Drioli

doi:10.2174/157017806779025942

ISSN: 1570-1786
E-ISSN: 1875-6255

An Efficient and Selective End-Modification of High-Molecular Weight Poly(Ethylene Glycol)s
Authors: Pietro Campaner¹, Gian Maria Bonora² and Sara Drioli³
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¹ Department of Chemical Science, University of Trieste, via Giorgieri 1, 34127 Trieste, Italy. ² Department of Chemical Science, University of Trieste, via Giorgieri 1, 34127 Trieste, Italy. ³ Department of Chemical Science, University of Trieste, via Giorgieri 1, 34127 Trieste, Italy.
Source: Letters in Organic Chemistry, Volume 3, Issue 10, Oct 2006, p. 773 - 779
DOI: https://doi.org/10.2174/157017806779025942
- Available online: 01 Oct 2006

Abstract

An innovative procedure aimed to the production of orthogonally protected amino-derivatives of high-molecular weight poly(ethylene glycol) (PEG) modified with linkers bearing differently reactive terminal amino groups is reported. This polymeric derivative represents a convenient, new soluble support particularly suitable as a drug delivery system of mixed molecules.

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2006-10-01

2025-09-17

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Article Type: Research Article

Keyword(s): conjugates; drug delivery; PEG; peptide; Poly(ethylene glycol); polymer

An Efficient and Selective End-Modification of High-Molecular Weight Poly(Ethylene Glycol)s

Abstract

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