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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Highlights in Organic Chemistry [Recent Advances in the Field of Peptide Nucleic Acids]
- Source: Letters in Organic Chemistry, Volume 3, Issue 7, Jul 2006, p. 495 - 503
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- 01 Jul 2006
Abstract
Since their development, peptide nucleic acids (PNAs) have attracted much attention as potential pharmacological regulators of gene expression. Currently, applications of PNAs are restricted through deficiencies in target specificity, aqueous solubility and cellular uptake. This highlight reviews syntheses and hybridisation properties of recent PNA analogues designed to address these limitations..
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