Highlights in Organic Chemistry Phase Vanishing" Method-System for Diffusion Controlled Addition of Exothermic Reagents Through a Fluorous Membrane

Fluorous solvent in "phase-vanishing" reactions acts as a phase screen between the bulk reagent and the reaction phase. The unique properties of the fluorous phase enable the slow diffusion-controlled transport of reagent through this bulk membrane and its uniform phase-transition from transport to reaction phase. Slow addition through the whole interface prevents the build-up of localised high concentration of reagent which means that it is possible to perform reactions involving highly reactive reagents at room temperature.