Efficient Chemical Synthesis of Sialic Acid Related Oligosaccharides

C. Zhao; X. Zhen; H. Zhang; Y. Ding

doi:10.2174/1570178054640732

ISSN: 1570-1786
E-ISSN: 1875-6255

Efficient Chemical Synthesis of Sialic Acid Related Oligosaccharides
Authors: C. Zhao¹, X. Zhen², H. Zhang³ and Y. Ding⁴
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¹ School of Chemistry and Chemical Engineering, Zhongshan Unversity, Guangzhou, P. R. China; ² School of Chemistry and Chemical Engineering, Zhongshan Unversity, Guangzhou, P. R. China; ³ School of Chemistry and Chemical Engineering, Zhongshan Unversity, Guangzhou, P. R. China; ⁴ School of Chemistry and Chemical Engineering, Zhongshan Unversity, Guangzhou, P. R. China;
Source: Letters in Organic Chemistry, Volume 2, Issue 6, Sep 2005, p. 521 - 523
DOI: https://doi.org/10.2174/1570178054640732
- Available online: 01 Sep 2005

Abstract

A very efficient strategy for the chemical synthesis of the sialyl Lewis X tetrasaccharide is reported. Starting from four simple monosaccharide building blocks, sialyl Lewis X was obtained in seven steps. By using similar strategy, sialyl LacNAc and sulfated sialyl LacNAc trisaccharides were also synthesized.

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2005-09-01

2025-09-02

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Article Type: Review Article

Keyword(s): hydrogenation; inflammation; monosaccharide; sialylation; tetrasaccharide

Efficient Chemical Synthesis of Sialic Acid Related Oligosaccharides

Abstract

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