Three Components Coupling Catalysed by Na2CaP2O7: Synthesis of α-Amino Phosphonates Under Solvent-Free Conditions at Room Temperature

M. Zahouily; A. Elmakssoudi; A. Mezdar; A. Rayadh; S. Sebti; H. B. Lazrek

doi:10.2174/1570178054405887

ISSN: 1570-1786
E-ISSN: 1875-6255

Three Components Coupling Catalysed by Na2CaP2O7: Synthesis of α-Amino Phosphonates Under Solvent-Free Conditions at Room Temperature
Authors: M. Zahouily¹, A. Elmakssoudi², A. Mezdar³, A. Rayadh⁴, S. Sebti⁵ and H. B. Lazrek⁶
View Affiliations Hide Affiliations

¹ Laboratoire de Catalyse, Chimiometrie et Environnement, UFR de Chimie Appliquee, Faculte des Sciences et Techniques, Universite Hassan II, Mohammedia B. P. 146, 20650 Maroc. ² Laboratoire de Catalyse, Chimiometrie et Environnement, UFR de Chimie Appliquee, Faculte des Sciences et Techniques, Universite Hassan II, Mohammedia B. P. 146, 20650 Maroc. ³ Laboratoire de Catalyse, Chimiometrie et Environnement, UFR de Chimie Appliquee, Faculte des Sciences et Techniques, Universite Hassan II, Mohammedia B. P. 146, 20650 Maroc. ⁴ Laboratoire de Catalyse, Chimiometrie et Environnement, UFR de Chimie Appliquee, Faculte des Sciences et Techniques, Universite Hassan II, Mohammedia B. P. 146, 20650 Maroc. ⁵ Laboratoire de Catalyse, Chimiometrie et Environnement, UFR de Chimie Appliquee, Faculte des Sciences et Techniques, Universite Hassan II, Mohammedia B. P. 146, 20650 Maroc. ⁶ Laboratoire de Catalyse, Chimiometrie et Environnement, UFR de Chimie Appliquee, Faculte des Sciences et Techniques, Universite Hassan II, Mohammedia B. P. 146, 20650 Maroc.
Source: Letters in Organic Chemistry, Volume 2, Issue 5, Aug 2005, p. 428 - 432
DOI: https://doi.org/10.2174/1570178054405887
- Available online: 01 Aug 2005

Abstract

Synthetic phosphate Na2CaP2O7 has been utilized as an efficient catalyst for the three components coupling of carbonyl compounds, aromatic and aliphatic amines and dialkyl phosphite to produce α-amino phosphonates. The reaction was carried out under solvent-free conditions at room temperature. The by-product H2O formed during the reaction increases the catalytic activity of Na2CaP2O7.

Article metrics loading...

/content/journals/loc/10.2174/1570178054405887

2005-08-01

2025-09-11

From This Site

/content/journals/loc/10.2174/1570178054405887

dcterms_title,dcterms_subject,pub_keyword

-contentType:Contributor -contentType:Concept -contentType:Institution

10

5

Full text loading...

/content/journals/loc/10.2174/1570178054405887

Article Type: Review Article

Keyword(s): amino phosphonates; heterogeneous catalysis; recyclable catalyst; synthetic phosphate

Three Components Coupling Catalysed by Na2CaP2O7: Synthesis of α-Amino Phosphonates Under Solvent-Free Conditions at Room Temperature

Abstract

From This Site

Most Read This Month

Most Cited Most Cited RSS feed

Vilsmeier-Haack Cyclisation as a Facile Synthetic Route to Thieno [2,3- b] Quinolines (Part I)

Efficient Synthesis of 4-Arylmethylene-3-methylisoxazol-5(4H)-one Derivatives Catalyzed by Malic Acid

Wonderful Natural Drugs with Surprising Nutritional Values, Rheum Species, Gifts of the Nature

Novel Derivatives Based on Zerumbone Scaffold as Potential Anticancer Inhibitors

A Review on the Syntheses and Applications of the 5H-chromeno[2,3- b]pyridines

Fe Doped Ga2O3 Nanomaterial Catalysed Green and Efficient One Pot Three Component Synthesis of Tetrahydrobenzo[b]pyran

Sulfonated Ethylenediamine Functionalized Magnetic Nanoparticles as a Highly Efficient Heterogeneous Nanocatalyst for the Green Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones

K2CO3/TBAB, a Composite of Inorganic and Organic Salts, a Novel and Powerful Media for Regioselective Michael Addition of Dihydropyrimidinones to Acrylic Esters Under and Without Solvent Conditions

Decomposition Kinetics of 1,1-Dihydroperoxycyclohexane in Some Organic Solvents

In Silico Screening of Some Anti-Cancer Drugs Against the Main Protease of COVID-19 Using Molecular Docking