Effect of Additional Chiral Ligands in Catalytic Enantioselective Addition of Ketene Silyl Acetals to Nitrones

P. Merino; S. Franco; P. Jimenez; T. Tejero; M. A. Chiacchio

doi:10.2174/1570178054038803

ISSN: 1570-1786
E-ISSN: 1875-6255

Effect of Additional Chiral Ligands in Catalytic Enantioselective Addition of Ketene Silyl Acetals to Nitrones
Authors: P. Merino¹, S. Franco², P. Jimenez³, T. Tejero⁴ and M. A. Chiacchio⁵
View Affiliations Hide Affiliations

¹ Departamento de Quimica Organica, Facultad de Ciencias-ICMA, Universidad de Zaragoza-CSIC, E-50009 Zaragoza, Aragón, Spain. ² Departamento de Quimica Organica, Facultad de Ciencias-ICMA, Universidad de Zaragoza-CSIC, E-50009 Zaragoza, Aragón, Spain. ³ Departamento de Quimica Organica, Facultad de Ciencias-ICMA, Universidad de Zaragoza-CSIC, E-50009 Zaragoza, Aragón, Spain. ⁴ Departamento de Quimica Organica, Facultad de Ciencias-ICMA, Universidad de Zaragoza-CSIC, E-50009 Zaragoza, Aragón, Spain. ⁵ Departamento de Quimica Organica, Facultad de Ciencias-ICMA, Universidad de Zaragoza-CSIC, E-50009 Zaragoza, Aragón, Spain.
Source: Letters in Organic Chemistry, Volume 2, Issue 4, Jun 2005, p. 302 - 305
DOI: https://doi.org/10.2174/1570178054038803
- Available online: 01 Jun 2005

Abstract

The enantioselectivity of the titanium (IV)-BINOL catalyzed asymmetric Mannich-type reactions of nitrones can be enhanced by using additional chiral ligands. The best results are obtained with diols derived from D-mannitol.

Article metrics loading...

/content/journals/loc/10.2174/1570178054038803

2005-06-01

2025-09-13

From This Site

/content/journals/loc/10.2174/1570178054038803

dcterms_title,dcterms_subject,pub_keyword

-contentType:Contributor -contentType:Concept -contentType:Institution

10

5

Full text loading...

/content/journals/loc/10.2174/1570178054038803

Article Type: Review Article

Keyword(s): aminoacids; hydroxylamines; mannich reaction; nitrones

Effect of Additional Chiral Ligands in Catalytic Enantioselective Addition of Ketene Silyl Acetals to Nitrones

Abstract

From This Site

Most Read This Month

Most Cited Most Cited RSS feed

Vilsmeier-Haack Cyclisation as a Facile Synthetic Route to Thieno [2,3- b] Quinolines (Part I)

Efficient Synthesis of 4-Arylmethylene-3-methylisoxazol-5(4H)-one Derivatives Catalyzed by Malic Acid

Wonderful Natural Drugs with Surprising Nutritional Values, Rheum Species, Gifts of the Nature

Novel Derivatives Based on Zerumbone Scaffold as Potential Anticancer Inhibitors

A Review on the Syntheses and Applications of the 5H-chromeno[2,3- b]pyridines

Fe Doped Ga2O3 Nanomaterial Catalysed Green and Efficient One Pot Three Component Synthesis of Tetrahydrobenzo[b]pyran

Sulfonated Ethylenediamine Functionalized Magnetic Nanoparticles as a Highly Efficient Heterogeneous Nanocatalyst for the Green Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones

K2CO3/TBAB, a Composite of Inorganic and Organic Salts, a Novel and Powerful Media for Regioselective Michael Addition of Dihydropyrimidinones to Acrylic Esters Under and Without Solvent Conditions

Decomposition Kinetics of 1,1-Dihydroperoxycyclohexane in Some Organic Solvents

In Silico Screening of Some Anti-Cancer Drugs Against the Main Protease of COVID-19 Using Molecular Docking