Reaction Systems Peripheral to the 1:2 Mannich Condensation Reaction between o-Phthalaldehyde and Primary Amine

I. Takahashi; K. Nishiuchi; R. Miyamoto; M. Hatanaka; H. Uchida; K. Isa; A. Sakushima; S. Hosoi

doi:10.2174/1570178053400216

ISSN: 1570-1786
E-ISSN: 1875-6255

Reaction Systems Peripheral to the 1:2 Mannich Condensation Reaction between o-Phthalaldehyde and Primary Amine
Authors: I. Takahashi¹, K. Nishiuchi², R. Miyamoto³, M. Hatanaka⁴, H. Uchida⁵, K. Isa⁶, A. Sakushima⁷ and S. Hosoi⁸
View Affiliations Hide Affiliations

¹ Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan. ² Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan. ³ Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan. ⁴ Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan. ⁵ Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan. ⁶ Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan. ⁷ Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan. ⁸ Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan.
Source: Letters in Organic Chemistry, Volume 2, Issue 1, Feb 2005, p. 40 - 43
DOI: https://doi.org/10.2174/1570178053400216
- Available online: 01 Feb 2005

Abstract

Reaction systems peripheral to the 1:2 condensation reaction between o-phthalaldehyde and primary amine were studied. Newly identified were 1,3-dihydroxyisoindoline, o-iminomethylbenzaldehyde and oamidiniobenzoate, the last of which exhibited moderate anticancer activity.

Article metrics loading...

/content/journals/loc/10.2174/1570178053400216

2005-02-01

2025-09-03

From This Site

/content/journals/loc/10.2174/1570178053400216

dcterms_title,dcterms_subject,pub_keyword

-contentType:Contributor -contentType:Concept -contentType:Institution

10

5

Full text loading...

/content/journals/loc/10.2174/1570178053400216

Article Type: Review Article

Keyword(s): 1,3-dihydroxyisoindoline; anticancer activity; o-amidiniobenzoate; o-iminomethylbenzaldehyde

Reaction Systems Peripheral to the 1:2 Mannich Condensation Reaction between o-Phthalaldehyde and Primary Amine

Abstract

From This Site

Most Read This Month

Most Cited Most Cited RSS feed

Vilsmeier-Haack Cyclisation as a Facile Synthetic Route to Thieno [2,3- b] Quinolines (Part I)

Efficient Synthesis of 4-Arylmethylene-3-methylisoxazol-5(4H)-one Derivatives Catalyzed by Malic Acid

Wonderful Natural Drugs with Surprising Nutritional Values, Rheum Species, Gifts of the Nature

Novel Derivatives Based on Zerumbone Scaffold as Potential Anticancer Inhibitors

A Review on the Syntheses and Applications of the 5H-chromeno[2,3- b]pyridines

Fe Doped Ga2O3 Nanomaterial Catalysed Green and Efficient One Pot Three Component Synthesis of Tetrahydrobenzo[b]pyran

Sulfonated Ethylenediamine Functionalized Magnetic Nanoparticles as a Highly Efficient Heterogeneous Nanocatalyst for the Green Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones

K2CO3/TBAB, a Composite of Inorganic and Organic Salts, a Novel and Powerful Media for Regioselective Michael Addition of Dihydropyrimidinones to Acrylic Esters Under and Without Solvent Conditions

Decomposition Kinetics of 1,1-Dihydroperoxycyclohexane in Some Organic Solvents

In Silico Screening of Some Anti-Cancer Drugs Against the Main Protease of COVID-19 Using Molecular Docking