Syntheses and Biological Activities of Novel N-tert-butyl-N'-Alkoxycarbonyl- N-Substituted Benzoylhydrazines and their Derivatives

A series of novel N-tert-butyl-N'-alkoxycarbonyl-N-substitutedbenzoylhydrazines and their derivatives were synthesized. The results of bioassay showed that these title compounds exhibit moderate larvicidal activities, and toxicity assays indicated that these title compounds can induce a premature, abnormal and lethal larval molt. At the same time, we found by chance that these title compounds possess potential anticancer activities in vitro.