Isoquinoline Alkaloids from Duguetia Vallicola Stem Bark with Antiplasmodial Activity

E. Perez; J. Saez; S. Blair; X. Franck; B. Figadere

doi:10.2174/1570178043488743

ISSN: 1570-1786
E-ISSN: 1875-6255

Isoquinoline Alkaloids from Duguetia Vallicola Stem Bark with Antiplasmodial Activity
Authors: E. Perez¹, J. Saez², S. Blair³, X. Franck⁴ and B. Figadere⁵
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¹ Institute of Chemistry, Universidad de Antioquia, P.O. Box 1226, Medellin-Colombia. ² Institute of Chemistry, Universidad de Antioquia, P.O. Box 1226, Medellin-Colombia. ³ Institute of Chemistry, Universidad de Antioquia, P.O. Box 1226, Medellin-Colombia. ⁴ Institute of Chemistry, Universidad de Antioquia, P.O. Box 1226, Medellin-Colombia. ⁵ Institute of Chemistry, Universidad de Antioquia, P.O. Box 1226, Medellin-Colombia.
Source: Letters in Organic Chemistry, Volume 1, Issue 1, Jan 2004, p. 102 - 104
DOI: https://doi.org/10.2174/1570178043488743
- Available online: 01 Jan 2004

Abstract

Duguevalline (1), a novel aporphinoid alkaloid, in addition to four known alkaloids, cleistopholine (2), O-methylmoschatoline (3), (-)-oliveroline (4) and (-)-oliveridine (5), were isolated and characterized from Duguetia vallicola stems. Structural elucidation of these compounds was established by spectroscopic methods. Among them, alkaloids (2) and (4) exhibited antiplasmodial activity against Plasmodium falciparum.

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2004-01-01

2025-10-04

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Article Type: Review Article

Keyword(s): annonaceae; antiplasmodial; duguetia vallicola; isoquinoline alkaloids

Isoquinoline Alkaloids from Duguetia Vallicola Stem Bark with Antiplasmodial Activity

Abstract

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