Synthesis and Isomerization of 3-Pyrroline Enamines

A. G. Cook; Karen A. Switek; Kenneth A. Cutler; Allison M. Witt

doi:10.2174/1570178043488734

ISSN: 1570-1786
E-ISSN: 1875-6255

Synthesis and Isomerization of 3-Pyrroline Enamines
Authors: A. G. Cook¹, Karen A. Switek², Kenneth A. Cutler³ and Allison M. Witt⁴
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¹ Department of Chemistry, Valparaiso University, Valparaiso, IN 46383, USA. ² Department of Chemistry, Valparaiso University, Valparaiso, IN 46383, USA. ³ Department of Chemistry, Valparaiso University, Valparaiso, IN 46383, USA. ⁴ Department of Chemistry, Valparaiso University, Valparaiso, IN 46383, USA.
Source: Letters in Organic Chemistry, Volume 1, Issue 1, Jan 2004, p. 1 - 5
DOI: https://doi.org/10.2174/1570178043488734
- Available online: 01 Jan 2004

Abstract

3-Pyrroline reacts with cyclic ketones to form enamines as kinetically controlled products. Under more vigorous conditions, pyrroles are formed as thermodynamically controlled products by way of a 1,3- hydride shift.

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2004-01-01

2025-10-05

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Article Type: Review Article

Keyword(s): enamine; isomerization; pyrrole; pyrroline

Synthesis and Isomerization of 3-Pyrroline Enamines

Abstract

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