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image of Palladium-Catalyzed Regioselective Alkenylation of Flavone Derivatives

Abstract

In this study, we present a palladium-catalyzed regioselective alkenylation protocol of flavones at the C3 position. A variety of functional groups, such as ether, ester, and halogen, are tolerated in this transformation, providing moderate to good yields. The proposed method offers a practical solution for the alkenylation of flavone in a step- and atom-economical manner, which has potential applications in the functionalization of biologically important flavone scaffolds in fields such as pharmaceuticals, food, and organic synthesis.

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/content/journals/loc/10.2174/0115701786434502251119063917
2026-01-15
2026-02-27
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