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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Ultrasound Irradiation Promoted Large-Scale Preparation in Aqueous Media and Antioxidant Activity of Azoles
- Source: Letters in Drug Design & Discovery, Volume 6, Issue 5, Jul 2009, p. 323 - 326
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- 01 Jul 2009
Abstract
The scaled-up preparation of 1H-pyrazole, 1-phenylpyrazole and isoxazole via sonocatalysis is reported. The products were isolated in good yields in short time reaction. These compounds had been assayed for antioxidant activity by ORAC and DPPH methodologies. The results showed that only 1-phenylpyrazole presented good antioxidant activity compared with Trolox®.
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