Full text loading...
- ISSN: 1570-1808
- E-ISSN: 1875-628X
-
Synthesis and Biological Evaluation of Novel Bioisosteric Analogues of Dimebon™
- Source: Letters in Drug Design & Discovery, Volume 7, Issue 6, Jul 2010, p. 446 - 451
-
- 01 Jul 2010
Abstract
In the present paper, we describe the synthesis and biological evaluation for a series of novel 6,9-disubstituted 2-methyl-1,2,3,4,5,6-hexahydroazepino[4,3-b]indoles. These compounds represent unique bioisosteric analogues of Dimebon ™ with promising biological activity against a panel of various targets including some GPCR family members.
© Bentham Science Publishers