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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Synthesis and Anticoccidial Activity of 3-(2-(1-methoxynaphthalen-2-yl)-2-oxoethyl) Quinazolinone Derivatives
- Source: Letters in Drug Design & Discovery, Volume 7, Issue 6, Jul 2010, p. 471 - 475
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- 01 Jul 2010
Abstract
A series of 3-(2-(1-methoxynaphthalen-2-yl)-2-oxoethyl) quinazolinone derivatives (8a-k) were designed and synthesized. Their anticoccidial activities were evaluated against Eimeria tenella in vivo. The results indicated that compounds 8a, 8b and 8e exhibited anticoccidial activity against Eimeria tenella in the chicken's diet with a dose of 18 mg/Kg.
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