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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Quantitative Structure Activity Relationship of Indole-Carbaldehyde Derivatives as Cannabinoid Receptor 2 Agonists
- Source: Letters in Drug Design & Discovery, Volume 6, Issue 8, Dec 2009, p. 599 - 619
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- 01 Dec 2009
Abstract
QSAR has been established for 73 Indole-carbaldehyde derivatives acting as Cannabinoid receptor 2 agonists. The best model was developed using six descriptors from topological, thermodynamic, spatial and electrotopological class. The model had r2 value of 0.888, PRESS value of 7.825, XV r2 value of 0.841 and test set correlation value 0.881.
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