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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Oleoylethanolamide: a Molecular Cross-Talk with Leptin in Feeding Behaviour Regulation
- Source: Letters in Drug Design & Discovery, Volume 3, Issue 10, Dec 2006, p. 741 - 746
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- 01 Dec 2006
Abstract
Oleoylethanolamide is an endogenous lipid mediator that reduces food intake and decreases body weight gain in rodents. As in leptin, oleoylethanolamide has a central and peripheral anorexic effect. In this article, we describe common potential targets, suggesting a molecular cross-talk between leptin and oleoylethanolamide which may regulate feeding behaviour.
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