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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Glycosyl Phosphatidylinositol-Anchored Proteins and HIV Infection
- Source: Letters in Drug Design & Discovery, Volume 3, Issue 9, Nov 2006, p. 598 - 604
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- 01 Nov 2006
Abstract
In addition to CD4 and chemokine receptors glycosyl phosphatidylinositol-anchored proteins (GPIAPs) have been involved in the regulation of the human immunodeficiency virus (HIV) life cycle. In this article we will review the mechanisms underlying the anti-HIV activities regulated by GPI-APs and their ligands. Understanding how GPI-APs finely regulate HIV infection and replication may unravel novel and complementary strategies to combat and control HIV infection.
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