Cytotoxicity of Native Sponges and Plants from the Colombian Caribbean Coast Against “Crown Gall” Tumors Induced by Agrobacterium tumefaciens

Fredyc Diaz; Ricardo Gaitan; Delfina Urbina; Ketty Mendoza; Marta Puello; Gregorio Torres; Eduardo de Avila

doi:10.2174/157018006778341129

ISSN: 1570-1808
E-ISSN: 1875-628X

Cytotoxicity of Native Sponges and Plants from the Colombian Caribbean Coast Against “Crown Gall” Tumors Induced by Agrobacterium tumefaciens
Authors: Fredyc Diaz¹, Ricardo Gaitan², Delfina Urbina³, Ketty Mendoza⁴, Marta Puello⁵, Gregorio Torres⁶ and Eduardo de Avila⁷
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¹ Calle 28 # 21-128 Apto 104 Edificio Barbacoas, Cartagena de Indias, Colombia, South America. ² Calle 28 # 21-128 Apto 104 Edificio Barbacoas, Cartagena de Indias, Colombia, South America. ³ Calle 28 # 21-128 Apto 104 Edificio Barbacoas, Cartagena de Indias, Colombia, South America. ⁴ Calle 28 # 21-128 Apto 104 Edificio Barbacoas, Cartagena de Indias, Colombia, South America. ⁵ Calle 28 # 21-128 Apto 104 Edificio Barbacoas, Cartagena de Indias, Colombia, South America. ⁶ Calle 28 # 21-128 Apto 104 Edificio Barbacoas, Cartagena de Indias, Colombia, South America. ⁷ Calle 28 # 21-128 Apto 104 Edificio Barbacoas, Cartagena de Indias, Colombia, South America.
Source: Letters in Drug Design & Discovery, Volume 3, Issue 9, Nov 2006, p. 640 - 644
DOI: https://doi.org/10.2174/157018006778341129
- Available online: 01 Nov 2006

Abstract

Agrobacterium tumefaciens is a Gram-negative rod able to induce crown-gall-like tumors in the potato discs. The cytotoxicity of extracts from Tabebuia and Xetospongia spp. was evaluated using this model. Two out of the six extracts tested (dichloromethane- and partial methanol-soluble extracts of Xetospongias spp.) showed the highest biological activity.

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2006-11-01

2025-09-25

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Article Type: Research Article

Keyword(s): Agrobacterium tumefaciens; Solanum tuberosum and cytotoxicity; Tabebuia spp; Ti plasmidum; Xetospongias spp

Cytotoxicity of Native Sponges and Plants from the Colombian Caribbean Coast Against “Crown Gall” Tumors Induced by Agrobacterium tumefaciens

Abstract

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