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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Improved Sensory Blockade by Clonidine Added to Axillary Block Solution. Resulting Plasma Clonidine Concentration
- Source: Letters in Drug Design & Discovery, Volume 3, Issue 2, Mar 2006, p. 87 - 90
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- 01 Mar 2006
Abstract
In this prospective, randomized, double-blinded study, clonidine was found an efficient adjunct to local anesthetics for increasing the intensity of axillary brachial plexus block. Similar clonidine dose had no such effect when administered intramuscularly, suggesting a local, neural effect. Blood absorption was similar in both cases, leading to central action as sedation.
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