Amide Mono Thioxylated Derivatives of MEN 10627

M. Altamura; G. Balacco; A. Giolitti; A. Guidi; R. Patacchini; A. R. Renzetti; A. Triolo; C. A. Maggi

doi:10.2174/1570180043398966

ISSN: 1570-1808
E-ISSN: 1875-628X

Amide Mono Thioxylated Derivatives of MEN 10627
Authors: M. Altamura¹, G. Balacco², A. Giolitti³, A. Guidi⁴, R. Patacchini⁵, A. R. Renzetti⁶, A. Triolo⁷ and C. A. Maggi⁸
View Affiliations Hide Affiliations

¹ Menarini Ricerche S.p.A.Via dei Sette Santi 3, 50131, Florence, Italy ² Menarini Ricerche S.p.A.Via dei Sette Santi 3, 50131, Florence, Italy ³ Menarini Ricerche S.p.A.Via dei Sette Santi 3, 50131, Florence, Italy ⁴ Menarini Ricerche S.p.A.Via dei Sette Santi 3, 50131, Florence, Italy ⁵ Menarini Ricerche S.p.A.Via dei Sette Santi 3, 50131, Florence, Italy ⁶ Menarini Ricerche S.p.A.Via dei Sette Santi 3, 50131, Florence, Italy ⁷ Menarini Ricerche S.p.A.Via dei Sette Santi 3, 50131, Florence, Italy ⁸ Menarini Ricerche S.p.A.Via dei Sette Santi 3, 50131, Florence, Italy
Source: Letters in Drug Design & Discovery, Volume 1, Issue 3, Jul 2004, p. 285 - 288
DOI: https://doi.org/10.2174/1570180043398966
- Available online: 01 Jul 2004

Abstract

The thioxylation of the potent Neurokinin A antagonist MEN 10627 by Lawesson's reagent showed to be potentially useful for the post-synthetic manipulation of the related family of structurally peculiar bicyclic hexapeptides, whose synthesis in combinatorial manner has been recently described.

Article metrics loading...

/content/journals/lddd/10.2174/1570180043398966

2004-07-01

2025-09-28

From This Site

/content/journals/lddd/10.2174/1570180043398966

dcterms_title,dcterms_subject,pub_keyword

-contentType:Contributor -contentType:Concept -contentType:Institution

10

5

Full text loading...

/content/journals/lddd/10.2174/1570180043398966

Article Type: Review Article

Keyword(s): anti-ischaemic drugs; atp; lawesson reagent; tachykinins; thiopeptides; thioxopeptides

Amide Mono Thioxylated Derivatives of MEN 10627

Abstract

From This Site

Most Read This Month

Most Cited Most Cited RSS feed

Discovery, Structural Determination and Anticancer Activities of Lactucinlike Guaianolides

Thermodynamic Aspects of Cancer: Possible Role of Negative Entropy in Tumor Growth, its Relation to Kinetic and Genetic Resistance

Immunomodulatory Properties of Synthetic Imidazolone Derivatives

Design and Prediction of ADME/Tox Properties of Novel Magnolol Derivatives as Anticancer Agents for NSCLC Using 3D-QSAR, Molecular Docking, MOLCAD and MM-GBSA Studies

Redox Active Iron at the Center of Oxidative Stress in Alzheimer Disease

Identifying Protein Binding Sites and Optimal Ligands

Phenyldihydroxypyrimidines as HCV NS5B RNA Dependent RNA Polymerase Inhibitors. Part I: Amides and Ureas

Phenyldihydroxypyrimidines as HCV NS5B RNA Dependent RNA Polymerase Inhibitors. Part II: Sulfonamides

Selection of a Catalytically Active Enzyme In Vivo Via Phage Display of its Product

A Comprehensive Review of the Advancement in Omic Technologies in the Field of Drug Discovery and Development