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2000
Volume 1, Issue 4
  • ISSN: 1570-1808
  • E-ISSN: 1875-628X

Abstract

Conjugates containing nigrin b (two-chain RIP) linked to a new lectin (SELld) from Sambucus ebulus L. have been designed. They retain the anti-ribosomal inhibitory activity of nigrin b but, in contrast to nigrin b, they exerted strong cytotoxicity on COLO 320 and HeLa cells, which ran in parallel with DNA fragmentation.

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/content/journals/lddd/10.2174/1570180043398687
2004-10-01
2025-09-04
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