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2000
Volume 25, Issue 8
  • ISSN: 1871-5265
  • E-ISSN: 2212-3989

Abstract

Aims/Introduction

This research aims to develop an advanced deep-learning framework for detecting respiratory diseases, including COVID-19, pneumonia, and tuberculosis (TB), using chest X-ray scans.

Methods

A Deep Neural Network (DNN)-based system was developed to analyze medical images and extract key features from chest X-rays. The system leverages various DNN learning algorithms to study X-ray scan color, curve, and edge-based features. The Adam optimizer is employed to minimize error rates and enhance model training.

Results and Discussion

A dataset of 1800 chest X-ray images, consisting of COVID-19, pneumonia, TB, and typical cases, was evaluated across multiple DNN models. The highest accuracy was achieved using the VGG19 model. The proposed system demonstrated an accuracy of 94.72%, with a sensitivity of 92.73%, a specificity of 96.68%, and an F1-score of 94.66%. The error rate was 5.28% when trained with 80% of the dataset and tested on 20%. The VGG19 model showed significant accuracy improvements of 32.69%, 36.65%, 42.16%, and 8.1% over AlexNet, GoogleNet, InceptionV3, and VGG16, respectively. The prediction time was also remarkably low, ranging between 3 and 5 seconds.

Conclusion

The proposed deep learning model efficiently detects respiratory diseases, including COVID-19, pneumonia, and TB, within seconds. The method ensures high reliability and efficiency by optimizing feature extraction and maintaining system complexity, making it a valuable tool for clinicians in rapid disease diagnosis.

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2025-05-27
2026-01-05
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References

  1. BernheimA. MeiX. HuangM. Chest CT findings in coronavirus disease-19 (COVID-19): Relationship to duration of infection.Radiology2020295320046310.1148/radiol.202020046332077789
    [Google Scholar]
  2. Coronavirus disease (COVID-19) Epidemiological updates and monthly operational updates.2025Available from:https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports/
  3. ShiF. WangJ. ShiJ. Review of artificial intelligence techniques in imaging data acquisition, segmentation and diagnosis forCOVID-19.IEEE Rev. Biomed. Eng.2021141441510.1109/RBME.2020.298797532305937
    [Google Scholar]
  4. GoyalY JoshiA MehendaleA The role of imaging in the detection and management of COVID-19: A review.J Res Med Dent Sci202210110159
    [Google Scholar]
  5. ShinH.C. RothH.R. GaoM. Deep convolutional neural networks for computer-aided detection: Cnn architectures, dataset characteristics and transfer learning.IEEE Trans. Med. Imaging20163551285129810.1109/TMI.2016.252816226886976
    [Google Scholar]
  6. DasA.K. GhoshS. ThunderS. DuttaR. AgarwalS. ChakrabartiA. Automatic COVID-19 detection from X-ray images using ensemble learning with convolutional neural network.Pattern Anal. Appl.20212431111112410.1007/s10044‑021‑00970‑4
    [Google Scholar]
  7. SharmaS. Drawing insights from COVID-19-infected patients using CT scan images and machine learning techniques: A study on 200 patients.Environ. Sci. Pollut. Res. Int.20202729371553716310.1007/s11356‑020‑10133‑332700269
    [Google Scholar]
  8. CozziD. AlbanesiM. CavigliE. Chest X-ray in new coronavirus disease 2019 (COVID-19) infection: Findings and correlation with clinical outcome.Radiol. Med.2020125873073710.1007/s11547‑020‑01232‑932519256
    [Google Scholar]
  9. MangalA. KaliaS. RajgopalH. CovidAID: COVID-19 detection using chest X-ray.2020Available From: https://arxiv.org/pdf/2004.09803
    [Google Scholar]
  10. UcarF. KorkmazD. COVIDiagnosis-Net: Deep bayes-squeezenet based diagnosis of the coronavirus disease 2019 (COVID-19) from X-ray images.Med. Hypotheses202014010976110.1016/j.mehy.2020.10976132344309
    [Google Scholar]
  11. JainS. ManochaA. Design and development of smart monitoring module for detection of virus, Measurement.Sensors20211610004810.1016/j.measen.2021.100048
    [Google Scholar]
  12. RahimzadehaM. AbolfazlAttar. A modified deep convolutional neural network for detecting COVID-19 and pneumonia from chest X-ray images based on the concatenation of Xception andResNet50V2.Inform. Med. Unlocked20201910036010.1016/j.imu.2020.10036032501424
    [Google Scholar]
  13. ToğaçarM. ErgenB. CömertZ. COVID-19 detection using deep learning models to exploit Social Mimic Optimization and structured chest X-ray images using fuzzy color and stacking approaches.Comput. Biol. Med.2020121June10380510.1016/j.compbiomed.2020.10380532568679
    [Google Scholar]
  14. OzturkT. TaloM. YildirimE.A. BalogluU.B. YildirimO.U. Rajendra Acharya. Automated detection of COVID-19 cases using deep neural networks with X-rayimages.Comput. Biol. Med.2020121June10379210.1016/j.compbiomed.2020.10379232568675
    [Google Scholar]
  15. AhujaS. PanigrahiB.K. DeyN. RajinikanthV. GandhiT.K. Deep transfer learning-based automated detection of COVID-19 from lung CT scan slices.Appl. Intell.202151157158510.1007/s10489‑020‑01826‑w34764547
    [Google Scholar]
  16. PurohitK. KesarwaniA. Ranjan KiskuD. DaluiM. COVID-19 detection on chest X-Ray and CT scan images using multi-image augmented deep learning model.Proceedings of the seventh international conference on mathematics and computing advances in intelligent systems and computing395-41310.1007/978‑981‑16‑6890‑6_30
    [Google Scholar]
  17. RodolfoM. COVID-19 identification in chest X-ray images on flat and hierarchical classification scenarios.Comput. Methods Prog Biomed.2020194October105532
    [Google Scholar]
  18. KaurP. HarnalS. TiwariR. A hybrid convolutional neural network model for diagnosis of COVID-19 using chest X-ray images.Int. J. Environ. Res. Public Health202118221219110.3390/ijerph18221219134831960
    [Google Scholar]
  19. ChauhanH. GuptaD. GuptaS. Blockchain enabled transparent and anti-counterfeiting supply of COVID-19 vaccine vials.Vaccines2021911123910.3390/vaccines911123934835170
    [Google Scholar]
  20. Tariq MahmoodM. SharmaG. MiglaniN. SinghA. AlharbiA. AlosaimiW. An intelligent fine-tuned forecasting technique for covid-19 prediction using neuralprophet model.Comput. Mater. Continua202271162964910.32604/cmc.2022.021884
    [Google Scholar]
  21. SinghP. SoodS. KumarY. PaprzyckiM. PljonkinA. HongW.C. Futuristic trends in networks and computing technologies.ChamSpringer Singapore20201810.1007/978‑981‑15‑4451‑4
    [Google Scholar]
  22. JindalH. SinghH. BhartiM. Modified cuckoo search for resource allocation on social internet-of-things. 2018 fifth international conference on parallel, distributed and grid computing (PDGC).201810.1109/PDGC.2018.8745772
    [Google Scholar]
  23. van der WaltS. ColbertS.C. VaroquauxG. The Numpy array: A structure for efficient numerical computation.Comput. Sci. Eng.2011132223010.1109/MCSE.2011.37
    [Google Scholar]
  24. ModyM. GhoneC. MathewM. JonesJ. Efficient frequency domain CNN algorithm.IEEE International Conference on Consumer Electronics-Asia (ICCE-Asia).2017
    [Google Scholar]
  25. ChangJ. ShaJ. An efficient implementation of 2d convolution in cnn.IEICE Electron. Express2016141310.1587/elex.13.20161134
    [Google Scholar]
  26. AhmadiM. VakiliS. LangloisJ.P. GrossW. Power reduction in cnn pooling layers with a preliminary partial computation strategy.2018 16th IEEE International New Circuits and Systems Conference (NEWCAS).201810.1109/NEWCAS.2018.8585433
    [Google Scholar]
  27. KoB. KimH-G. OhK-J. ChoiH-J. Controlled dropout: A different approach to usingdropout on deep neural network.2017 IEEE International Conference on Big Data and Smart Computing (BigComp)IEEE, 2017, pp. 358-362.
    [Google Scholar]
  28. BhardwajC. JainS. SoodM. Transfer learning based robust automatic detection system for diabetic retinopathy grading.Neural Comput. Appl.20213320139991401910.1007/s00521‑021‑06042‑2
    [Google Scholar]
  29. BhardwajC. JainS. SoodM. Deep learning based diabetic retinopathy severity grading system employing quadrant ensemble model.J. Digit. Imaging202134244045710.1007/s10278‑021‑00418‑533686525
    [Google Scholar]
  30. WenL. LiX. LiX. GaoL. A New Transfer learning based on VGG-19 networkfor fault diagnosis.2019 IEEE 23rd International Conference on Computer Supported Cooperative Work in Design (CSCWD).201910.1109/CSCWD.2019.8791884
    [Google Scholar]
  31. BhartiM. JindalH. Modified genetic algorithm for resource selection on internet of things. International conference on futuristic trends in networks and computing technologies.2019, pp. 164-176.
    [Google Scholar]
  32. BhardwajC. JainS. SoodM. Diabetic retinopathy severity grading employing quadrant‐based Inception‐V3 convolution neural network architecture.Int. J. Imaging Syst. Technol.202131259260810.1002/ima.22510
    [Google Scholar]
  33. JainS. SaxenaS. SinhaS. Ensemble architecture for prediction of grading of diabetic retinopathy.Cybern. Syst.20225582235225310.1080/01969722.2022.2151176
    [Google Scholar]
  34. BhardwajC. JainS. SoodM. Two-tier grading system for NPDR severities of diabetic retinopathy in retinal fundus images.Recent Pat. Eng.202115219520610.2174/1872212114666200109103922
    [Google Scholar]
  35. BhardwajC. JainS. SoodM. Hierarchical severity grade classification of non-proliferative diabetic retinopathy.J. Ambient Intell. Humaniz. Comput.20211222649267010.1007/s12652‑020‑02426‑9
    [Google Scholar]
  36. ZhangZ. Improved adam optimizer for deep neural networks.2018 IEEE/ACM 26th International Symposium on Quality of Service (IWQoS).201810.1109/IWQoS.2018.8624183
    [Google Scholar]
  37. DogoE. AfolabiO. NwuluN. TwalaB. AigbavboaC. A comparative analysis of gradient descent-based optimization algorithms on convolutional neural networks.2018 International Conference on Computational Techniques, Electronics and Mechanical Systems (CTEMS)2018, pp. 92-99.201810.1109/CTEMS.2018.8769211
    [Google Scholar]
  38. JindalH. SaxenaS. KasanaS.S. Triangular pyramidal topology to measure semporal and Spatial variations in shallow river water using Ad-hoc sensors network’.Ad Hoc Sens. Wirel. Netw.2017391-4135
    [Google Scholar]
  39. Covid-chestxray-dataset2020Available from:https://github.com/ieee8023/covid-chestxray-dataset/tree/master/images
  40. ApostolopoulosI.D. BessianaT. Covid-19: Automatic detection from X-ray images utilizing transfer learning with convolutional neural networks.Phys. Eng. Sci. Med.202043263564010.1007/s13246‑020‑00865‑4
    [Google Scholar]
  41. JindalH. BhartiM. KasanaS.S. SaxenaS. An ensemble mosaicing and ridgelet based fusion technique for underwater panoramic image reconstruction and its refinement.Multimedia Tools Appl.20238222337193377110.1007/s11042‑023‑14594‑9
    [Google Scholar]
  42. AggarwalA. JainS. JindalH. Computational model for the detection of diabetic retinopathy in 2-d color fundus retina scan.Curr. Med. Imaging2024201573405624818310.2174/011573405624818323101011193738333976
    [Google Scholar]
  43. HussainE. HasanM. RahmanM.A. LeeI. TamannaT. ParvezM.Z. CoroDet: A deep learning based classification for COVID-19 detection using chest X-ray images.Chaos Solitons Fractals202014211049510.1016/j.chaos.2020.11049533250589
    [Google Scholar]
  44. ZhaoB. ZhangX. ZhanZ. PangS. Deep multi-scale convolutional transfer learning network: A novel method for intelligent fault diagnosis of rolling bearings under variable working conditions and domains.Neurocomputing2020407243810.1016/j.neucom.2020.04.073
    [Google Scholar]
  45. BhardwajC. A computational framework for diabetic retinopathy severity grading categorization using ophthalmic image processing.Thesis, Jaypee University of Information Technology2020
    [Google Scholar]
  46. OhY. ParkS. YeJ.C. Deep learning COVID-19 features on CXR using limited training data sets.IEEE Trans. Med. Imaging20203982688270010.1109/TMI.2020.299329132396075
    [Google Scholar]
  47. KhanA.I. ShahJ.L. BhatM.M. CoroNet: A deep neural network for detection and diagnosis of COVID-19 from chest x-ray images.Comput. Methods Programs Biomed.202019610558110.1016/j.cmpb.2020.10558132534344
    [Google Scholar]
  48. KeedwellE. An analysis of the area under the ROC curve and its use as a metric for comparing clinical scorecards.2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)2014, pp. 24-29.10.1109/BIBM.2014.6999263
    [Google Scholar]
  49. AnthimopoulosM. ChristodoulidisS. EbnerL. ChristeA. MougiakakouS. Lung pattern classification for interstitial lung diseases using a deep convolutional neural network.IEEE transactions on medical imaging.2016 Feb 2935512071216
    [Google Scholar]
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  • Article Type:
    Research Article
Keyword(s): COVID-19; deep neural network; Pneumonia; respiratory diseases; tuberculosis; x-ray
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