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2000
Volume 25, Issue 7
  • ISSN: 1871-5265
  • E-ISSN: 2212-3989

Abstract

Introduction

The present study aimed to carry out the molecular identification of some bacteria in seminal fluid and investigation of their effects on semen quality.

Methods

The research cohort comprised 80 infertile individuals and 80 men with no fertility issues. Evaluation of sperm characteristics adhered to the protocols outlined by the World Health Organization. Detection and verification of pathogens were carried out by PCR.

Results and Discussion

The prevalence of bacteriospermia in the semen of the infertile group exhibited a noticeable increase compared to the control group (<0.05). The most abundant species in the semen of infertile men was (7.5%, <0.05), followed by (6.25%, >0.05). However, was not found in any of the abnormal samples. In addition, we showed that significantly affected the motility and morphology parameters. But, the presence of and in semen samples of men does not lead to abnormal sperm production. Besides, there was no significant difference between the groups in terms of volume, but there was a significant difference in morphology, count, and total motility (<0.001).

Conclusion

Bacteriospermia is linked to modifications in the characteristics of seminal fluid, potentially resulting in a reduction in the fertilization capacity of spermatozoa. Furthermore, is correlated with changes in semen properties that could contribute to a decrease in sperm fertilization potential.

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2025-02-24
2026-01-05

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/content/journals/iddt/10.2174/0118715265328194250213114956
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Molecular Detection of Ureaplasma urealyticum and Enterococcus faecalis in the Seminal Fluid and their Relationship with Semen Quality in Healthy and Infertile Men in Shiraz, Iran (2021-2022)
Infect. Disord. Drug Targets 25, E18715265328194 (2025); https://doi.org/10.2174/0118715265328194250213114956
/content/journals/iddt/10.2174/0118715265328194250213114956
/content/journals/iddt/10.2174/0118715265328194250213114956
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  • Article Type:     Research Article
Keyword(s): bacteriospermia; Enterococcus faecalis; Infertility; seminal fluid; Streptococcus agalactiae; Ureaplasma urealyticum

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