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2000
Volume 11, Issue 1
  • ISSN: 2215-0838
  • E-ISSN: 2215-0846
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Abstract

Background

The Cucurbitaceae family has been well-known since ancient times for its use in daily food preparations. Various traditional medicinal systems have also recognized its therapeutic importance. Its significance has also been established by modern techniques.

Objective

The current review aims to emphasize the glycosides of the Cucurbitaceae family in terms of their source, structures, extraction media, and bioactivities in various therapeutic areas like anti-inflammatory, anti-bacterial, anti-cancerous, anti-diabetic, and cardiac models. Glycosides of Cucurbitaceae have been studied extensively. However, considering the vastness of the diversity among this family; there are still various avenues in which further research work is needed.

Methods

For the present review, we used Elsevier-ScienceDirect, SpringerLink, PubMed, ArticlesPlus, Semantic Scholar, and Google Scholar to conduct a literature search.

Results

Cucurbitaceae is enriched with secondary metabolites, mainly glycosides. The occurrence of glycoside with its species, along with plant parts, is crucial and elaborately covered. It also captures the extraction system. The structure of selected glycosides is represented along with respective references. Various studies elaborate on the pharmacological significance of the extracts in diverse therapeutic areas.

Conclusion

This review provides extensive aspects about the glycosides of the family Cucurbitaceae and will help in further exploration of extraction, isolation, and bioactivity studies of this important class of compounds from one of the largest families, ., Cucurbitaceae. It reiterates the need for further exploration in standardization along with extensive safety and efficacy studies.

2025 © 2025 The Author(s). Published by Bentham Science Publisher. The Author(s)
© 2025 The Author(s). Published by Bentham Science Publishers. This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode.
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2025-08-19

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/content/journals/ctm/10.2174/0122150838293392231227065022
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Cucurbitaceae Glycosides: An In-depth Review on its Source, Structural, and Medicinal Significance
Current Traditional Medicine 11, e120124225548 (2025); https://doi.org/10.2174/0122150838293392231227065022
/content/journals/ctm/10.2174/0122150838293392231227065022
/content/journals/ctm/10.2174/0122150838293392231227065022
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  • Article Type:     Review Article
Keyword(s): Biological activity; cucurbitaceae; extraction; flavonoids; glycosides; phytochemistry; saponins

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