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2000
Volume 11, Issue 3
  • ISSN: 2215-0838
  • E-ISSN: 2215-0846

Abstract

Background

(Dalzell) Oliv. belongs to Rutaceae family and it is native to South and Southeast Asia. The plant is used in the traditional medicine to treat malaria, rheumatism, bone fracture .

Objective

In the present review, the previous reports on concerning its ethnobotanical uses, morphological description, eco-geographical features, phytochemistry and pharmacological effects are summarized.

Methods

ScienceDirect, PubMed, Springer, Scopus and Google Scholar were used to find potentially relevant literature. The collected literature was analyzed and potential titles were included for screening the abstracts and checking the full texts. After screening 90 potentially interesting articles and other related literature, a reference list of about 39 articles was selected. The reviews, dissertations and other literature without any original research were excluded.

Results

Investigation on the phytochemical compounds has revealed the presence of coumarins, furanocoumarins, sesquiterpenes, flavonoids, phenolic compounds and carbazole alkaloids. The essential oils and fractions isolated from were validated for pharmacological properties such as antioxidant, antidiabetic, anti-leukemic, antimicrobial and free radical scavenging effects.

Conclusion

The present review describes the ethnomedicinal uses, reported phytochemical compounds isolated from the plant species and various pharmacological properties of . Ethnomedicinal studies indicated the use of for the treatment of various diseases. Pharmacological reports showed that exhibited significant antidiabetic, antioxidant, antimicrobial, free radical scavenging, anti-gout and anticancer effects. Detailed phytochemical studies and molecular gene expression studies are required to explain the exact mechanism of action of active phytocompounds.

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