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Current Topics in Chemistry - Volume 4, Issue 1, 2024

Volume 4, Issue 1

Volume 4, Issue 1, 2024

    • Trifolirhizin from as a Promising Medicinal Agent: An Update on Biological Significance, Pharmacological Activity, and Analytical Applications

      https://doi.org/10.2174/0126660016285747240830061418

      is an important medicinal plant found in India and East Asia, primarily in China, Japan, Korea and Russia. Trifolirhizin is an active phytochemical of and other Chinese medications such as Zeng-Sheng-Ping, Xian-Lian-Ke-Li, ASHMI, Ling Zhi, Ku Shen, and Gan Cao, Ku Shen injection and Zeng Sheng Ping tablets. have numerous therapeutic benefits against hematochezia, jaundice, liver disorders, dysentery, oliguria, asthma, eczema, vulvar swelling, and inflammatory complications. The purpose of the present review is to summarize the scientific information on trifolirhizin for their biological potential, pharmacological activities, and analytical aspects. Scientific information on trifolirhizin has been collected from various scientific databases such as Scopus, Science Direct, PubMed, and Google Scholar. Further, the present review summarized the pharmacological activities of trifolirhizin and their different molecular mechanisms and analytical aspects. The scientific data on trifolirhizin signified the biological potential and therapeutic effectiveness of trifolirhizin in medicine. Present review signified the presence of trifolirhizin in the . has been shown to be effective against ulcers, chronic bronchitis, acne, atopic dermatitis, chronic hepatitis, enteritis, pyogenic infection and other inflammatory diseases. Furthermore, the present review also summarized the biological potential of trifolirhizin in gastric cancer, hepatocellular carcinoma, colorectal cancer, apoptosis, ulcerative colitis, and asthma. However, hepatoprotective effects, anti-inflammatory effects, wound healing potential, and efficiency of melanin synthesis were also revealed. In addition, this review also summarizes the molecular mechanisms of trifolirhizin and their pharmacokinetic and metabolic parameters. This review also describes the analytical aspects of trifolirhizin in medicine. This review will be useful to the entire research community exploring the biological potential of trifolirhizin in medicine. However, scientific studies require comprehensive and detailed data on trifolirhizin evaluation, quality control, toxicity, and clinical efficacy.

    • Micro-Milli Scale for the Removal of Iron and Copper by a Positively Charged Foam before Nickel Colorimetric Detection using Handy Spectrometer

      https://doi.org/10.2174/0126660016300603240528050146
      Introduction

      A simple alternative removal of iron and copper before the determination of nickel was proposed. The procedure was based on sampling a milligram sample and a micro-milliliter operation.

      Methods

      The method has been applied to jewelry items. A 50 mg sample was digested by 5 mL of nitric acid with heating. The obtained solution was added to KSCN before passing through polyurethane foam (PUF) (1 cm i.d. × 8 cm length). Some metal ions-SCN complexes (, Fe(III) and Cu(II)) were retained in the column while Ni(II) ions were kept in the eluate. A 200-500 µL aliquot was added with 4-(2-pyridylazo)-resorcinol (PAR) as the color reagent. At least 30 µL of a portion was measured for the absorbance of the color product using a handy spectrometer.

      Results

      The positively charged foam could remove iron and copper altogether before determining nickel. A standard calibration was a plot of absorbance versus Ni(II) concentration for 1-30 mg/L: Absorbance = 0.0123 [Ni(II), mg/L] + 0.0435 (R2=0.9945) with a limit of detection (LOD) and limit of quantitation (LOQ) of 0.24 mg/L and 0.81 mg/L, respectively. Two bracelet samples showed the presence of nickel at 0.97 ± 0.25 and 0.27 ± 0.04 mg/g, respectively, and agreed with the reference FlameAAS method.

      Conclusion

      The proposed method could be used to assay nickel in samples containing high levels of iron and copper, such as jewelry. This will benefit general wearers with health concerns associated with nickel, particularly in case of inexpensive accessories. The handy spectrometer used in the study might make be helpful to carry out these studies with a limited tight budget.

    • Emerging Role of Ionic Liquids in the Fabric Industry

      https://doi.org/10.2174/0126660016287413240306115111

      Profitable interest in the pervasive packaging of ionic liquids has continued to increase due to its several advantages and environmentally pleasant nature. Fabric enterprise is stated to be the most important enterprise as a result of a rapid increase in the populace across the globe. Certain ionic beverages can dissolve textile fibers. Therefore, ionic liquids are doubtlessly appropriate for material production and recycling. The dyeing of fabric substances involves numerous financial and ecological risks, resulting in an excessive intake of water, power, and chemicals. Ionic liquids surpass through their extraordinarily low vapor pressure, which enables them to deal with commonly used natural solvents. Moreover, ionic liquids display excessive temperature-associated dielectric constants, consequently displaying top-notch solvent strength for distinct fabric-associated substances, inclusive of silicones, keratin, and cellulose. This article provides a brief review of the pertinent literature that focuses on historical patterns and practical commercial applications of ionic liquids before moving on to current developments in ionic liquids and the fabric industry.

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