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2000
Volume 20, Issue 5
  • ISSN: 1574-888X
  • E-ISSN: 2212-3946

Abstract

Breast milk plays an important role in preventing and remission various acute and chronic neonatal diseases. However, the mechanisms through which breast milk performs these effects are still unclear. Recently, research has shown that breast milk contains previously undiscovered cells, called breast milk stem cells (BMSCs), which have the potential for multiple differentiation. These cells have been shown to be expressed in multiple organs and systems of infants after ingestion. This study found that newborns who received BMSCs required a shorter treatment duration and had a better prognosis than those who did not receive BMSCs. This suggests that BMSCs may be able to treat a variety of neonatal diseases, and breast milk may play a role in preventing and mitigating neonatal diseases through BMSCs. In this paper, we summarized the research progress on BMSCs and their therapeutic effects on organs, the possible ways in which BMSCs enter different organs and tissues of the human body, and detailed the types of diseases, modes of action, and mechanisms that BMSCs may play a role in. We aim to pave the way for further clinical and preclinical research on BMSCs, as well as the treatment of neonatal diseases with BMSCs, to provide possible new therapeutic means for treating neonatal diseases and a variety of other diseases.

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2024-06-03
2025-11-04

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/content/journals/cscr/10.2174/011574888X304788240526190336
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Breast Milk Stem Cells in the Treatment of Neonatal Diseases
Curr Stem Cell Res Ther 20, 538 (2025); https://doi.org/10.2174/011574888X304788240526190336
/content/journals/cscr/10.2174/011574888X304788240526190336
/content/journals/cscr/10.2174/011574888X304788240526190336
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  • Article Type:     Review Article
Keyword(s): breast milk stem cells; exosomes; hypoxic-ischemic encephalopathy; mesenchymal stem cells; necrotizing enterocolitis; Newborn; preterm infants

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