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image of Bioactive Phytochemicals: Unlocking the Promise of Natural Remedies for Diabetes Mellitus

Abstract

Background

Metabolic syndrome encompasses conditions such as diabetes mellitus (DM), which has become increasingly prevalent. Chemically synthesized medications are commonly used to mitigate the effects of DM and its complications; however, these often result in undesirable side effects, including weight gain, digestive issues, and heart failure.

Objective

This review highlights the therapeutic potential of bioactive compounds and anti-diabetic plants that possess proven anti-diabetic properties. Focusing on phytomedicines also explores their possible mechanisms of action and positions this work relative to current reviews in the field.

Methods

A comprehensive literature analysis was conducted, emphasizing the therapeutic potential of bioactive compounds in anti-diabetic plants. Databases such as PubMed, Scopus, and Google Scholar were thoroughly searched to identify studies investigating the anti-diabetic properties and mechanisms of action of plant-derived bioactive compounds. Inclusion criteria focused on studies evaluating the pharmacological effects of herbal medicines, plant extracts, and isolated bioactive compounds on diabetes management.

Results

Therapeutic plants, as sources of anti-diabetic compounds, offer significant advantages. They are affordable, exhibit minimal or no adverse effects, and do not necessitate strict dietary restrictions or intense exercise regimens. The integrated insights underscore the potential of phytomedicines to address limitations in current diabetes management strategies.

Conclusion

The unique focus on phytomedicines positions this review as a valuable resource for researchers and clinicians. Detailing mechanisms and evidence supporting the efficacy of these compounds, guides the development of innovative strategies for identifying and utilizing bioactive compounds in effective diabetes management.

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2025-04-03
2025-10-07

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Bioactive Phytochemicals: Unlocking the Promise of Natural Remedies for Diabetes Mellitus
Bentham Science Publishers ; https://doi.org/10.2174/0113892010371753250324150813
/content/journals/cpb/10.2174/0113892010371753250324150813
/content/journals/cpb/10.2174/0113892010371753250324150813
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  • Article Type:     Review Article
Keywords: phytoconstituents ; pancreatic β-cells ; anti-diabetic agents ; natural remedies ; Diabetes mellitus ; herbal drugs ; insulin

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