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2000
Volume 26, Issue 8
  • ISSN: 1389-2010
  • E-ISSN: 1873-4316

Abstract

Cancer remains a significant global health challenge, necessitating innovative approaches to enhance the efficacy and specificity of therapeutic interventions while minimizing adverse effects on healthy tissues. Nanotechnology has emerged as a promising avenue in cancer treatment, offering novel strategies for targeted drug delivery. Nanoparticles, liposomes, and polymer-based systems have played pivotal roles in revolutionizing cancer therapy. Nanotechnology possesses unique physicochemical properties, enabling efficient encapsulation of therapeutic agents and controlled and prolonged release at tumour sites. Advancement in formulations using nanotechnology has made it possible to make multifunctional systems that respond to the microenvironment of a tumour by releasing payloads in response to changes in pH, temperature, or enzymes. Stimuli-responsive polymers can release drugs in response to external cues, enabling site-specific drug release and minimizing systemic exposure. This review explores recent studies and preclinical trials that show how nanoparticles, liposomes, and polymer-based systems could be used to treat cancer, discussing challenges such as scalability, regulatory approval, and potential toxicity concerns along with patents published recently.

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2025-10-03

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/content/journals/cpb/10.2174/0113892010279483240417050548
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Nanotechnology Integrated Innovative Drug Delivery and Therapy for Cancer
Current Pharmaceutical Biotechnology 26, 1189 (2025); https://doi.org/10.2174/0113892010279483240417050548
/content/journals/cpb/10.2174/0113892010279483240417050548
/content/journals/cpb/10.2174/0113892010279483240417050548
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  • Article Type:     Review Article
Keyword(s): dendrimers; liposomes; nanoparticles; Nanotechnology; polymer-based systems; targeted drug delivery; therapeutic outcomes

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