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2000
Volume 7, Issue 1
  • ISSN: 2666-7967
  • E-ISSN: 2666-7975

Abstract

Introduction

The purpose of this study was to investigate the demographic, clinical, and laboratory risk factors associated with mortality in Coronavirus disease 2019 (COVID-19) patients who were admitted to the intensive care unit (ICU) in Iran.

Materials & Methods

This retrospective study analyzed data from 867 COVID-19 patients admitted to the ICU of Shahid Beheshti Hospital in Hamadan (west of Iran) from September 2020 to March 2022. The association between demographic, clinical, and laboratory factors and mortality rates was assessed using univariable and multiple logistic regression analysis.

Results

During the study period, 512 (59.1%) patients were deceased from COVID-19. According to the adjusted logistic regression, the odds of death in patients with an age higher than 60 years were 1.12 (95% CI: 1.01- 1.24; =0.026). The OR estimate of death in patients with bradycardia and tachycardia was 2.32 (95% CI: 1.72- 3.12; < 0.001) and 2.40 (95% CI: 1.67- 3.42; < 0.001), respectively. Moreover, SPO lower than 88%, WBC over 11 ×1000µL, K over 5.2 mEq/L, and LDH above 942 U/L were significantly associated with increased odds of death ( < 0.05).

Conclusion

The study identified several demographic, clinical, and laboratory risk factors associated with mortality in COVID-19 patients admitted to the ICU in Iran. These findings can help healthcare providers identify patients at higher risk of poor outcomes and tailor interventions accordingly.

© 2026 Bentham Science Publishers
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2024-09-20
2026-01-03

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Clinical and Laboratory Factors Associated with Mortality in ICU-Hospitalized COVID-19 Patients in a Western Center of Iran
Coronaviruses 7, E26667975323582 (2026); https://doi.org/10.2174/0126667975323582240911070005
/content/journals/covid/10.2174/0126667975323582240911070005
/content/journals/covid/10.2174/0126667975323582240911070005
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  • Article Type:     Research Article
Keyword(s): Clinical factors; COVID-19; intensive care unit; laboratory factors; mortality; respiratory distress syndrome

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