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- ISSN: 1385-2728
- E-ISSN: 1875-5348
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An Efficient Ligandless Palladium-catalyzed Protocol for Suzuki-Miyaura Coupling Reaction of Potassium Aryltrifluoroborates in Water
- Source: Current Organic Chemistry, Volume 22, Issue 20, Sep 2018, p. 2023 - 2028
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- 01 Sep 2018
Abstract
An efficient and ligandless catalytic system was developed for the Suzuki- Miyaura coupling reactions of potassium aryltrifluoroborates in pure water. Using TEAB as additives, Pd(OAc)2 was found to be very efficient for the Suzuki-Miyaura coupling of potassium aryltrifluoroborates with various aryl and heteroaryl bromides in pure water with Na2CO3 as a base, affording the desired products in moderate to excellent yields.
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