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The 2008 Catalysis/Natural Product Chemistry issue of Current Organic Chemistry contains two contributions from eminent scientists in different field. Professor Sartori and coworkers review the use of organic solid supported base as cataliyst in organic synthesis in the last decade. The synthesis of α-amino ketones are of great importance in organic synthesis. Professor Cancellon and her group provide an overview of the literature reported methods for the synthesis and synthetic application of this type of compounds. I would like to express my sincere thanks to all the authors for providing these articles and for the fascinating results described.