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image of Insights into the Synthesis and Bioactivity of Indole-Based Compounds: A Short Review

Abstract

Indole derivatives are a significant class of organic compounds with diverse biological activities. They are found in numerous natural products and synthetic drugs, playing a crucial role in medicinal chemistry. In this comprehensive review, we have summarized the synthetic approaches and biological evaluations of a variety of indole derivatives. We analyzed and studies assessing the bioactivity of indole derivatives, focusing on structure-activity relationships. The versatility and efficacy of indole-based compounds hold great potential for advancing medical therapies, particularly in the fields of cancer treatment, infectious diseases, and inflammatory disorders. This concise review aims to inspire further research on indole-based compounds for drug development.

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2025-07-02
2025-11-06

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Insights into the Synthesis and Bioactivity of Indole-Based Compounds: A Short Review
Bentham Science Publishers ; https://doi.org/10.2174/0113852728382848250610051815
/content/journals/coc/10.2174/0113852728382848250610051815
/content/journals/coc/10.2174/0113852728382848250610051815
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  • Article Type:     Review Article
Keywords: melatonin ; Indole derivatives ; pharmacological properties ; heterocycles ; synthetic strategies ; structure-activity relationship

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