Skip to content
2000
image of The Genus Chisocheton: An Extensive Review of Phytochemistry and Pharmacology

Abstract

is a genus of woody trees in the family Meliaceae. Due to the appearance of numerous bioactive compounds, it was widely used in traditional medicines. The current research aims to provide an extensive overview of phytochemical and pharmacological values. To find the English references, a thorough search of numerous electronic data sources, such as Web of Science, PubMed, Google Scholar, and Science Direct, was conducted. The “Sci-Finder” was used to confirm chemical structures and references. Documents that have been cited date back to the 1970s. The best keywords for the collection of articles are “”, “phytochemistry”, and “pharmacology”. Phytochemical investigations of extracts led to the separation of more than 270 secondary metabolites. They included limonoids, triterpenoids, sesquiterpenoids, phytosterols, chirol-inositols, flavonoids, and others. Various compounds were new in the literature. constituents possessed various pharmacological activities, including cytotoxicity, anti-inflammatory, antioxidative, antidiabetic, anti-obesity, antibacterial, antimalarial, tyrosinase inhibitory, mosquito larvicidal, and neuroprotective activities. Some compounds are better than standard agents in biological experiments. Apoptosis is the main pathway of anticancer compounds, whereas cytokine inhibition may be attributed to their anti-inflammatory actions. The studied genus is a good source of limonoids, terpenoids, and phytosterols with various pharmacological potentials.

© 2025 Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/coc/10.2174/0113852728382432250527075453
2025-06-27
2025-10-14

  • From This Site

    /content/journals/coc/10.2174/0113852728382432250527075453
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

References

  1. Shilpi J.A. Saha S. Chong S.L. Nahar L. Sarker S.D. Awang K. Advances in chemistry and bioactivity of the genus Chisocheton Blume. Chem. Biodivers. 2016 13 5 483 503 10.1002/cbdv.201400373 26970405
    [Google Scholar]
  2. Fisher J.B. Indeterminate leaves of Chisocheton (Meliaceae): Survey of structure and development. Bot. J. Linn. Soc. 2002 139 2 207 221 10.1046/j.1095‑8339.2002.00050.x
    [Google Scholar]
  3. Orosa R.L. Tree Of the month Balukanag - Chisocheton cumingianus (C. DC.) harms. Available from: https://www.philstar.com/cebu-news/2012/12/24/889513/tree-month-part2-balukanag-chisocheton-cumingianus
  4. Harneti D. Salam S. Nurlelasari Maharani R. Mayanti T. Safari A. Hidayat A.T. Lesmana R. Fajriah S. Supratman U. Prescott T. Shiono Y. Pentandricines F-H, cytotoxic limonoids from the stem bark of Chisocheton pentandrus (Blanco) Merr. Phytochem. Lett. 2023 54 119 124 10.1016/j.phytol.2023.02.005
    [Google Scholar]
  5. Mohamad K. Hirasawa Y. Lim C.S. Awang K. Hadi A.H.A. Takeya K. Morita H. Ceramicine A and walsogyne A, novel limonoids from two species of Meliaceae. Tetrahedron Lett. 2008 49 27 4276 4278 10.1016/j.tetlet.2008.04.145
    [Google Scholar]
  6. Ngadni M.A. Chong S.L. Kamarudin M.N.A. Hazni H. Litaudon M. Supratman U. Awang K. Erythrocarpines I N, new limonoids from the barks of Chisocheton erythrocarpus and their neuroprotective effects against hydrogen peroxide in NG108–15 cells. Fitoterapia 2024 173 105765 10.1016/j.fitote.2023.105765 38042506
    [Google Scholar]
  7. Inada A. Somekawa M. Murata H. Nakanishi T. Tokuda H. Nishino H. Iwashima A. Darnaedi D. Murata J. Phytochemical studies on meliaceous plants. VIII. Structures and inhibitory effects on Epstein-Barr virus activation of triterpenoids from leaves of Chisocheton macrophyllus King. Chem. Pharm. Bull. (Tokyo) 1993 41 3 617 619 10.1248/cpb.41.617
    [Google Scholar]
  8. Huang S.S. Jian K.L. Li R.J. Kong L.Y. Yang M.H. Phytosteroids and triterpenoids with potent cytotoxicities from the leaves of Chisocheton cumingianus. RSC Advances 2016 6 8 6320 6328 10.1039/C5RA23626F
    [Google Scholar]
  9. Katja D.G. Farabi K. Nurlelasari Harneti D. Mayanti T. Supratman U. Awang K. Hayashi H. Cytototoxic constituents from the bark of Chisocheton cumingianus (Meliaceae). J. Asian Nat. Prod. Res. 2017 19 2 194 200 10.1080/10286020.2016.1196671 27329305
    [Google Scholar]
  10. Katja D.G. Farabi K. Nurlelasari N. Harneti D. Julaeha E. Hidayat A.T. Mayanti T. Maharani R. Supratman U. Awang K. Cytotoxic steroids from the stem bark of Chisocheton cumingianus (Meliaceae). Molekul 2017 12 1 1 7 10.20884/1.jm.2017.12.1.257
    [Google Scholar]
  11. Nguyen H.T. Tran L.T.T. Ho D.V. Phan K.V. Raal A. Morita H. Three new inositol derivatives from Chisocheton paniculatus. Tetrahedron Lett. 2019 60 28 1841 1844 10.1016/j.tetlet.2019.06.015
    [Google Scholar]
  12. Nguyen K.V. Ho D.V. Nguyen H.M. Do T.T. Phan K.V. Morita H. Heinämäki J. Raal A. Nguyen H.T. Chiro-inositol derivatives from Chisocheton paniculatus showing inhibition of nitric oxide production. J. Nat. Prod. 2020 83 4 1201 1206 10.1021/acs.jnatprod.9b01239 32208696
    [Google Scholar]
  13. Hilmayanti E. Nurlelasari N. Katja D.G. Hidayat A.T. Fajriah S. Darmawan A. Supratman U. Azmi M.N. Shiono Y. Azadirone-type limonoids from the fruit of Chisocheton lasiocarpus and their cytotoxic activity against MCF-7 breast cancer lines. Molekul 2022 17 1 60 67 10.20884/1.jm.2022.17.1.5593
    [Google Scholar]
  14. Hilmayanti E. Huang X. Salam S. Nurlelasari Supratman U. Kabayama K. Fukase K. In vitro anti-inflammatory study of limonoids isolated from Chisocheton plants. Curr. Issues Mol. Biol. 2024 46 1 909 922 10.3390/cimb46010058 38275672
    [Google Scholar]
  15. Wang Z. Zhang P. Cui L. Li Q. Kong L. Luo J. Chisosiamens A–E, five new ring-intact limonoids with isomerized furan ring from the fruit of Chisocheton siamensis. Fitoterapia 2021 151 104873 10.1016/j.fitote.2021.104873 33662446
    [Google Scholar]
  16. Bordoloi M. Saikia B. Mathur R.K. Goswami B.N. A meliacin from Chisocheton paniculatus. Phytochemistry 1993 34 2 583 584 10.1016/0031‑9422(93)80054‑V
    [Google Scholar]
  17. Laphookhieo S. Maneerat W. Koysomboon S. Kiattansakul R. Chantrapromma K. Syers J.K. A novel limonoid from the seeds of Chisocheton siamensis. Can. J. Chem. 2008 86 3 205 208 10.1139/v07‑155
    [Google Scholar]
  18. Maneerat W. Laphookhieo S. Koysomboon S. Chantrapromma K. Antimalarial, antimycobacterial and cytotoxic limonoids from Chisocheton siamensis. Phytomedicine 2008 15 12 1130 1134 10.1016/j.phymed.2008.05.004 18617378
    [Google Scholar]
  19. Supratman U. Salam S. Naibaho W. Fajar M. Nurlelasari Katja D.G. Harneti D. Maharani R. Hidayat A.T. Lesmana R. Azlan Nafiah M. Shiono Y. New cytotoxic limonoids from the stem bark of Chisocheton pentandrus (Blanco) Merr. Phytochem. Lett. 2020 35 63 67 10.1016/j.phytol.2019.11.002
    [Google Scholar]
  20. Nurlelasari Rahmayanti I. Salam S. Safari A. Harneti D. Maharani R. Hidayat A.T. Tanjung M. Retnowati R. Shiono Y. Supratman U. A new havanensin-type limonoid from Chisocheton macrophyllus. Appl. Biol. Chem. 2021 64 1 35 10.1186/s13765‑021‑00606‑5
    [Google Scholar]
  21. Iijima C. Wong C.P. Nugroho A.E. Sotozono Y. Someya S. Hirasawa Y. Kaneda T. Hadi A.H.A. Morita H. Anti-melanin deposition activity of ceramicines from Chisocheton ceramicus. J. Nat. Med. 2016 70 4 702 707 10.1007/s11418‑016‑1016‑y 27357963
    [Google Scholar]
  22. Nugroho A.E. Hashimoto A. Wong C.P. Yokoe H. Tsubuki M. Kaneda T. Hadi A.H.A. Morita H. Ceramicines M–P from Chisocheton ceramicus: Isolation and structure–activity relationship study. J. Nat. Med. 2018 72 1 64 72 10.1007/s11418‑017‑1109‑2 28822030
    [Google Scholar]
  23. Nugroho A.E. Wong C.P. Hirasawa Y. Kaneda T. Tougan T. Horii T. Hadi A.H.A. Morita H. Antimalarial ceramicines Q-T from Chisocheton ceramicus. J. Nat. Med. 2023 77 3 596 603 10.1007/s11418‑023‑01706‑w 37162697
    [Google Scholar]
  24. Nugroho A.E. Komuro T. Kawaguchi T. Shindo Y. Wong C.P. Hirasawa Y. Kaneda T. Tougan T. Horii T. Hadi A.H.A. Morita H. Ceramicines U–Z from Chisocheton ceramicus and structure–antimalarial activity relationship study. J. Nat. Med. 2024 78 1 68 77 10.1007/s11418‑023‑01746‑2 37690111
    [Google Scholar]
  25. Gunning P.J. Jeffs L.B. Isman M.B. Towers G.H.N. Two limonoids from Chisocheton microcarpus. Phytochemistry 1994 36 5 1245 1248 10.1016/S0031‑9422(00)89645‑4
    [Google Scholar]
  26. Connolly J.D. Labbé C. Rycroft D.S. Taylor D.A.H. Tetranortriterpenoids and related compounds. Part 22. New apotirucailol derivatives and tetranortriterpenoids from the wood and seeds of Chisocheton paniculatus(meliaceae). J. Chem. Soc., Perkin Trans. 1 1979 1 0 2959 2964 10.1039/P19790002959
    [Google Scholar]
  27. Supriatno Nurlelasari Herlina T. Harneti D. Maharani R. Hidayat A.T. Mayanti T. Supratman U. Azmi M.N. Shiono Y. A new limonoid from stem bark of Chisocheton pentandrus (Meliaceae). Nat. Prod. Res. 2018 32 21 2610 2616 10.1080/14786419.2018.1428600 29368952
    [Google Scholar]
  28. Salam S. Harneti D. Maharani R. Nurlelasari Safari A. Hidayat A.T. Lesmana R. Nafiah M.A. Supratman U. Kyle Prescott T.A. Shiono Y. Cytotoxic triterpenoids from Chisocheton pentandrus. Phytochemistry 2021 187 112759 10.1016/j.phytochem.2021.112759 33839518
    [Google Scholar]
  29. Chong S.L. Hematpoor A. Hazni H. Sofian-Azirun M. Litaudon M. Supratman U. Murata M. Awang K. Mosquito larvicidal limonoids from the fruits of Chisocheton erythrocarpus Hiern. Phytochem. Lett. 2019 30 69 73 10.1016/j.phytol.2018.12.013
    [Google Scholar]
  30. Gaffar S. Hafiz E. Wiraswati H.L. Ishmayana S. Nurlelasari N. Dysobinol extracted from Chisocheton macrophyllus triggers proliferation inhibition, potential apoptosis, and cell cycle arrest of Hela cancer cell lines. Majalah Kedokteran Bandung 2024 56 1 35 41 10.15395/mkb.v56.3249
    [Google Scholar]
  31. Katja D.G. Hilmayanti E. Nurlelasari Mayanti T. Harneti D. Maharani R. Farabi K. Darwati Lesmana R. Fajriah S. Supratman U. Azmi M.N. Shiono Y. Limonoids from the fruits of Chisocheton lasiocarpus (Meliaceae). J. Asian Nat. Prod. Res. 2023 25 1 36 43 10.1080/10286020.2022.2032678 35128999
    [Google Scholar]
  32. Nurlelasari Parulian S.S. Naini A.A. Hilmayanti E. Farabi K. Harneti D. Darwati Mayanti T. Maharani R. Herlina T. Supratman U. Anwar R. Fajriah S. Azmi M.N. Prescott T. Shiono Y. Tirucallane-type triterpenoid from the stem bark of Chisocheton lasiocarpus and its cytotoxic activity against MCF-7 breast cancer cells. J. Asian Nat. Prod. Res. 2023 25 8 803 809 10.1080/10286020.2022.2143353 36409205
    [Google Scholar]
  33. Mohamad K. Hirasawa Y. Litaudon M. Awang K. Hadi A.H.A. Takeya K. Ekasari W. Widyawaruyanti A. Zaini N.C. Morita H. Ceramicines B–D, new antiplasmodial limonoids from Chisocheton ceramicus. Bioorg. Med. Chem. 2009 17 2 727 730 10.1016/j.bmc.2008.11.048 19081726
    [Google Scholar]
  34. Najmuldeen I.A. Hadi A.H.A. Awang K. Mohamad K. Ketuly K.A. Mukhtar M.R. Chong S.L. Chan G. Nafiah M.A. Weng N.S. Shirota O. Hosoya T. Nugroho A.E. Morita H. Chisomicines A-C, limonoids from Chisocheton ceramicus. J. Nat. Prod. 2011 74 5 1313 1317 10.1021/np200013g 21428417
    [Google Scholar]
  35. Najmuldeen I.A. Hadi A.H.A. Mohamad K. Awang K. Ketuly K.A. Mukhtar M.R. Taha H. Nordin N. Litaudon M. Guéritte F. Nugroho A.E. Morita H. Chisomicines D and E, Two new limonoids from Chisocheton ceramicus. Heterocycles 2012 84 2 1265 1270 10.3987/COM‑11‑S(P)31
    [Google Scholar]
  36. Najmuldeen I.A. Abdul Hadi A.H. Awang K. Mohamad K. Ng S.W. 14-Deoxyxyloccensin K from Chisocheton ceramicus (Meliaceae). Acta Crystallogr. Sect. E Struct. Rep. Online 2010 66 8 o1927 10.1107/S160053681002564X 21588256
    [Google Scholar]
  37. Awang K. Lim C.S. Mohamad K. Morita H. Hirasawa Y. Takeya K. Thoison O. Hadi A.H.A. Erythrocarpines A–E, new cytotoxic limonoids from Chisocheton erythrocarpus. Bioorg. Med. Chem. 2007 15 17 5997 6002 10.1016/j.bmc.2007.05.049 17576066
    [Google Scholar]
  38. Nagoor N.H. Shah Jehan Muttiah N. Soon Lim C. In L.L.A. Mohammad K. Awang K. Regulation of apoptotic effects by erythrocarpine E, a cytotoxic limonoid from Chisocheton erythrocarpus in HSC-4 human oral cancer cells. PLoS One 2011 6 8 e23661 10.1371/journal.pone.0023661 21858194
    [Google Scholar]
  39. Ngadni M.A. Chong S.L. Hazni H. Asib N. Ishak I.H. Mohmad Misnan N. Supratman U. Awang K. Limonoids from the fruits of Chisocheton erythrocarpus and their mosquito larvicidal activities. Phytochemistry 2024 222 114092 10.1016/j.phytochem.2024.114092 38604323
    [Google Scholar]
  40. Chong S.L. Awang K. Martin M.T. Mokhtar M.R. Chan G. Litaudon M. Gueritte F. Mohamad K. Malayanines A and B, two novel limonoids from Chisocheton erythrocarpus Hiern. Tetrahedron Lett. 2012 53 40 5355 5359 10.1016/j.tetlet.2012.07.067
    [Google Scholar]
  41. Yang M.H. Wang J.S. Luo J.G. Wang X.B. Kong L.Y. Tetranortriterpenoids from Chisocheton paniculatus. J. Nat. Prod. 2009 72 11 2014 2018 10.1021/np900485t 19943621
    [Google Scholar]
  42. Katja D.G. Farabi K. Nuraini V.A. Nurlelasari N. Hidayat A.T. Mayanti T. Harneti D. Supratman U. A new 30-nor trijugin-type limonoid, chisotrijugin, from the bark of Chisocheton cumingianus (Meliaceae). Int. J. Chem. 2016 8 3 30 34 10.5539/ijc.v8n3p30
    [Google Scholar]
  43. Phongmaykin J. Kumamoto T. Ishikawa T. Suttisri R. Saifah E. A new sesquiterpene and other terpenoid constituents of Chisocheton penduliflorus. Arch. Pharm. Res. 2008 31 1 21 27 10.1007/s12272‑008‑1115‑8 18277603
    [Google Scholar]
  44. Chan K.Y. Mohamad K. Ooi A.J.A. Imiyabir Z. Chung L.Y. Bioactivity-guided fractionation of the lipoxygenase and cyclooxygenase inhibiting constituents from Chisocheton polyandrus Merr. Fitoterapia 2012 83 5 961 967 10.1016/j.fitote.2012.04.018 22565147
    [Google Scholar]
  45. Xie B. Yang S. Zhang C. Yue J. Chisiamols A–F, Triterpenoids from Chisocheton siamensis. Chin. J. Chem. 2009 27 9 1805 1810 10.1002/cjoc.200990304
    [Google Scholar]
  46. Zhang F. He X.F. Wu W.B. Chen W.S. Yue J.M. New apotirucallane-type triterpenoids from Chisocheton paniculatus. Nat. Prod. Bioprospect. 2012 2 6 235 239 10.1007/s13659‑012‑0065‑5
    [Google Scholar]
  47. Yadav R.D. Kataky J.C.S. Mathur R.K. ChemInform abstract: New Protolimonoids and Limonoids. Part 2. Study of the stereochemistry of new tetranortriterpenoids isolated from the root-wood of Chisocheton paniculatus Hiern (Meliaceae). ChemInform 2000 31 40 chin.200040167 10.1002/chin.200040167
    [Google Scholar]
  48. Yadav R.D. Kataky J.C.S. Mathur R.K. ChemInform abstract: New protolimonoids and limonoids. Part 3. Arunachalin, a new tetranortriterpenoid from Chisocheton paniculatus Hiern (Meliaceae). ChemInform 1999 30 27 chin.199927204 10.1002/chin.199927204
    [Google Scholar]
  49. Yang M.H. Wang J.S. Luo J.G. Wang X.B. Kong L.Y. Chisopanins A–K, 11 new protolimonoids from Chisocheton paniculatus and their anti-inflammatory activities. Bioorg. Med. Chem. 2011 19 4 1409 1417 10.1016/j.bmc.2011.01.007 21288727
    [Google Scholar]
  50. Yang M.H. Wang J.S. Luo J.G. Wang X.B. Kong L.Y. Four new triterpenoids from Chisocheton paniculatus and their anti-inflammatory activities. Can. J. Chem. 2012 90 2 199 204 10.1139/v11‑147
    [Google Scholar]
  51. Hoai N.T. Duc H.V. Raal A. Morita H. A new limonoid from Chisocheton paniculatus fruit collected in Vietnam and its NO production inhibitory activity. Nat. Prod. Commun. 2018 13 10 1934578X1801301005 10.1177/1934578X1801301005
    [Google Scholar]
  52. Supratman U. Naibaho W. Salam S. Maharani R. Hidayat A.T. Harneti D. Nurlelasari Shiono Y. Cytotoxic triterpenoids from the bark of Chisocheton patens Blume (Meliaceae). Phytochem. Lett. 2019 30 81 87 10.1016/j.phytol.2019.01.034
    [Google Scholar]
  53. Nugroho A.E. Okabe M. Hirasawa Y. Wong C.P. Kaneda T. Tougan T. Horii T. Morita H. A novel trimeric triterpene from Chisocheton ceramics Miq. Nat. Prod. Commun. 2021 16 11 1934578X211053202 10.1177/1934578X211053202
    [Google Scholar]
  54. Nurlelasari Indriani S.S. Mayanti T. Farabi K. Safari A. Harneti D. Maharani R. Hidayat A.T. Supratman U. Katja D.G. Shiono Y. A new oleanane-type triterpenoid from the fruits of Chisocheton macrophyllus. Chem. Nat. Compd. 2023 59 1 76 79 10.1007/s10600‑023‑03922‑y
    [Google Scholar]
  55. Sari V.M. Nurlelasari Harneti D. maharani R. Indrayati N. Azmi M.N. Supratman U. Triterpenoid and steroid from the rind of Chisocheton macrophyllus (Meliaceae). J. Phys. Conf. Ser. 2020 1494 1 012025 10.1088/1742‑6596/1494/1/012025
    [Google Scholar]
  56. Fareza M.S. Nurlelasari M Supratman U. Katja D.G. 1,1,4,7-Tetramethyldecahydro-1H-cyclopropa[e]azulen-7-ol from the stembark Chisocheton pentandrus. Molbank 2019 2019 4 M1092 10.3390/M1092
    [Google Scholar]
  57. Supratman U. Sari A. Nurlelasari N. Azhari A. Harneti D. Maharani R. Mayanti T. Farabi K. Darwati D. Fajriah S. Azmi M.N. Shiono Y. New ergostane-type sterol produced by an endophytic fungus Fusarium phaseoli isolated from Chisocheton macrophyllus (Meliaceae). Rec. Nat. Prod. 2022 16 6 614 621 10.25135/rnp.334.2203.2387
    [Google Scholar]
  58. Najmuldeen I.A. Hadi A.H.A. Awang K. Mohamad K. Ng S.W. 17-(5-Ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1 H -cyclopenta[ a ]phenanthrene-3,7-diol from Chisocheton tomentosus ( Meliaceae ). Acta Crystallogr. Sect. E Struct. Rep. Online 2008 64 11 o2163 10.1107/S1600536808033163 21581023
    [Google Scholar]
  59. Najmuldeen I.A. Hadi A.H.A. Mohamad K. Awang K. Nasab M.F. Ketuly K.A. Mukhtar M.R. Morita H. Steroids from Chisocheton tomentosus. Malays. J. Sci. 2011 30 2 144 153 10.22452/mjs.vol30no2.9
    [Google Scholar]
  60. Sun Y. Wang Z. Hua W. Cui L. Kong L. Luo J. D-Chiro-inositol derivatives with multidrug resistance reversal activities from the fruits of Chisocheton siamensis. J. Nat. Prod. 2023 86 4 860 868 10.1021/acs.jnatprod.2c01033 37020426
    [Google Scholar]
  61. Fajar M. Salam S. Harneti D. Maharani R. Indrayati N. Katja D.G. Azmi M.N. Four flavan-3-ol compounds from the stem bark of Chisocheton balansae C.DC. (Meliaceae). Molekul 2021 16 1 9 15 10.20884/1.jm.2021.16.1.642
    [Google Scholar]
  62. Hidayat A.T. Nurlelasari N. Abdullah F.F. Harneti D. Maharani R. Haikal K. Supratman U. Azmi M.N. A new lignan derivative, lasiocarpone, from the stembark of Chisocheton iasiocarpus (Meliaceae). Orient. J. Chem. 2018 34 4 1956 1960 10.13005/ojc/3404032
    [Google Scholar]
  63. Tzouros M. Bigler L. Bienz S. Hesse M. Inada A. Murata H. Inatomi Y. Nakanishi T. Darnaedi D. Two new spermidine alkaloids from Chisocheton weinlandii. Helv. Chim. Acta 2004 87 6 1411 1425 10.1002/hlca.200490129
    [Google Scholar]
  64. Son N.T. The genus Walsura: A rich resource of bioactive limonoids, triterpenoids, and other types of compounds. Prog. Chem. Org. Nat. Prod. 2022 118 131 177 10.1007/978‑3‑030‑92030‑2_4 35416519
    [Google Scholar]
  65. Chung L.Y. Soo W.K. Chan K.Y. Mustafa M.R. Goh S.H. Imiyabir Z. Lipoxygenase inhibiting activity of some Malaysian plants. Pharm. Biol. 2009 47 12 1142 1148 10.3109/13880200903008724
    [Google Scholar]
  66. Wibawa I.P A H. Hanafi M. Minarti Li’aini A.S. Rahayu A. Semarayani C.I.M. Lugrayasa I.N. Butardo V.M. Mahon P.J. Chisocheton pentandrus (Blanco) Merr. leaf as a potential antioxidant and α-glucosidase inhibitory agent. IOP Conf. Ser. Earth Environ. Sci. 2024 1312 1 012054 10.1088/1755‑1315/1312/1/012054
    [Google Scholar]
  67. Wong C.P. Deguchi J. Nugroho A.E. Kaneda T. Hadi A.H.A. Morita H. Ceramicines from Chisocheton ceramicus as lipid-droplets accumulation inhibitors. Bioorg. Med. Chem. Lett. 2013 23 6 1786 1788 10.1016/j.bmcl.2013.01.037 23395661
    [Google Scholar]
  68. Hai T.Q. Huong N.T. Son N.T. The medicinal plant Peucedanum japonicum Thunberg: A review of traditional use, phytochemistry, and pharmacology. Fitoterapia 2024 179 106270 10.1016/j.fitote.2024.106270 39442677
    [Google Scholar]
  69. Thi Thoa N. Hop N.Q. Son N.T. Chloranthus japonicus Sieb. (Chloranthaceae): A review of metabolite structural diversity and pharmacology. Biochem. Syst. Ecol. 2024 117 104911 10.1016/j.bse.2024.104911
    [Google Scholar]
  70. Wong C.P. Kaneda T. Hadi A.H.A. Morita H. Ceramicine B, a limonoid with anti-lipid droplets accumulation activity from Chisocheton ceramicus. J. Nat. Med. 2014 68 1 22 30 10.1007/s11418‑013‑0755‑2 23494817
    [Google Scholar]
/content/journals/coc/10.2174/0113852728382432250527075453
Loading
The Genus Chisocheton: An Extensive Review of Phytochemistry and Pharmacology
Bentham Science Publishers ; https://doi.org/10.2174/0113852728382432250527075453
/content/journals/coc/10.2174/0113852728382432250527075453
/content/journals/coc/10.2174/0113852728382432250527075453
Loading

Data & Media loading...


  • Article Type:     Review Article
Keywords: limonoid ; phytochemistry ; pharmacology ; Meliaceae ; cytotoxicity ; Chisocheton

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test