Allium sativum L.: A Potent Functional Food with Potential Anticancer Properties

References

1. AhmedS. FahimJ. AbdelmohsenU. Chemical and biological studies on Allium sativum L. (1952-2020): A comprehensive review.J Adv Biomed Pharm Sci20225112210.21608/jabps.2021.90667.1137
   [Google Scholar]
2. El-SaadonyM.T. SaadA.M. KormaS.A. Garlic bioactive substances and their therapeutic applications for improving human health: A comprehensive review.Front. Immunol.202415127707410.3389/fimmu.2024.1277074 38915405
   [Google Scholar]
3. MoutiaM. HabtiN. BadouA. In vitro and in vivo immunomodulator activities of Allium sativum L.Evid. Based Complement. Alternat. Med.20182018498465910.1155/2018/4984659 30008785
   [Google Scholar]
4. Melguizo-RodríguezL. García-RecioE. RuizC. De Luna-BertosE. Illescas-MontesR. Costela-RuizV.J. Biological properties and therapeutic applications of garlic and its components.Food Funct.20221352415242610.1039/D1FO03180E 35174827
   [Google Scholar]
5. ChaurasiaP.K. BharatiS.L. SinghS. Garlic against heart-related ailments: Chemistry, pharmacology, and future perspective.Mini Rev. Med. Chem.202424552153010.2174/1389557523666230821102512 37605421
   [Google Scholar]
6. PandeyP. KhanF. AlshammariN. SaeedA. AqilF. SaeedM. Updates on the anticancer potential of garlic organosulfur compounds and their nanoformulations: Plant therapeutics in cancer management.Front. Pharmacol.202314115403410.3389/fphar.2023.1154034 37021043
   [Google Scholar]
7. SharmaV. SinhaE. SinghJ. Investigation of in-vitro anti-cancer and apoptotic potential of garlic-derived nanovesicles against prostate and cervical cancer cell lines.Asian Pac. J. Cancer Prev.202425257558510.31557/APJCP.2024.25.2.575 38415544
   [Google Scholar]
8. YangQ. LiF. JiaG. LiuR. Aged black garlic extract inhibits the growth of estrogen receptor-positive breast cancer cells by downregulating MCL-1 expression through the ROS-JNK pathway.PLoS One2023186e028645410.1371/journal.pone.0286454 37352173
   [Google Scholar]
9. YifanM. RuiX. YuanL. FeiyunJ. Allicin inhibits the biological activities of cervical cancer cells by suppressing circEIF4G2.Food Sci. Nutr.20241242523253610.1002/fsn3.3935 38628206
   [Google Scholar]
10. RavindraJ. UgY. PandyandaN.D. Allicin extracted from Allium sativum shows potent anti-cancer and antioxidant properties in zebrafish.Biomed. Pharmacother.202316911585410.1016/j.biopha.2023.115854 37951024
    [Google Scholar]
11. SavitriA.D. HidayatiH.B. VeteriniL. An in-silico study on allicin compound in garlic (Allium sativum) as a potential inhibitor of human epidermal growth factor receptor (Her)-2 positive breast cancer.Jordan J. Biol. Sci.202316171210.54319/jjbs/160102
    [Google Scholar]
12. Özkanİ. KoçakP. YıldırımM. Garlic (Allium sativum)-derived SEVs inhibit cancer cell proliferation and induce caspase mediated apoptosis.Sci. Rep.20211111477310.1038/s41598‑021‑93876‑4 34285262
    [Google Scholar]
13. KanamoriY. Dalla ViaL. MaconeA. Aged garlic extract and its constituent, S allyl L cysteine, induce the apoptosis of neuroblastoma cancer cells due to mitochondrial membrane depolarization.Exp. Ther. Med.20191921511152110.3892/etm.2019.8383 32010332
    [Google Scholar]
14. LiZ. LeW. CuiZ. A novel therapeutic anticancer property of raw garlic extract via injection but not ingestion.Cell Death Discov.20184110810.1038/s41420‑018‑0122‑x 30479841
    [Google Scholar]
15. SpecianiM.C. GargariG. PenaginiR. Garlic consumption in relation to colorectal cancer risk and to alterations of blood bacterial DNA.Eur. J. Nutr.20236252279229210.1007/s00394‑023‑03110‑2 37093261
    [Google Scholar]
16. ZhouX. QianH. ZhangD. ZengL. Garlic intake and the risk of colorectal cancer.Medicine2020991e1857510.1097/MD.0000000000018575 31895803
    [Google Scholar]
17. Bat-ChenW. GolanT. PeriI. LudmerZ. SchwartzB. Allicin purified from fresh garlic cloves induces apoptosis in colon cancer cells via Nrf2.Nutr. Cancer201062794795710.1080/01635581.2010.509837 20924970
    [Google Scholar]
18. SchwarzY. KindilL. Bar-ShaiA. RabinkovA. StarA. The active compound of garlic to treat non-small cell lung cancer: In vitro studies.Eur. Respir. J.201342Suppl. 573111
    [Google Scholar]
19. ChuY.L. HoC.T. ChungJ.G. RaghuR. LoY.C. SheenL.Y. Allicin induces anti-human liver cancer cells through the p53 gene modulating apoptosis and autophagy.J. Agric. Food Chem.201361419839984810.1021/jf403241s 24059278
    [Google Scholar]
20. GaoX. SanthanamR.K. HuangZ. Allicin-mediated cell cycle regulation reverses taxol resistance in NSCLC: Molecular insights and therapeutic potentia.J. Food Biochem.2023991043110.1155/2023/9910431
    [Google Scholar]
21. IshikawaH. SaekiT. OtaniT. Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.J. Nutr.20061363816S820S10.1093/jn/136.3.816S 16484572
    [Google Scholar]
22. PetrovicV. NepalA. OlaisenC. Anti-cancer potential of homemade fresh garlic extract is related to increased endoplasmic reticulum stress.Nutrients201810445010.3390/nu10040450 29621132
    [Google Scholar]
23. BrugnoliF. Dell’AiraM. TedeschiP. Effects of garlic on breast tumor cells with a triple negative phenotype: Peculiar subtype-dependent down-modulation of Akt Signaling.Cells2024131082210.3390/cells13100822 38786044
    [Google Scholar]
24. MondalA. BanerjeeS. BoseS. Garlic constituents for cancer prevention and therapy: From phytochemistry to novel formulations.Pharmacol. Res.202217510583710.1016/j.phrs.2021.105837 34450316
    [Google Scholar]
25. StępieńA.E. TrojniakJ. TabarkiewiczJ. Anti-cancer and anti-inflammatory properties of black garlic.Int. J. Mol. Sci.2024253180110.3390/ijms25031801 38339077
    [Google Scholar]
26. TalibW.H. BabanM.M. AzzamA.O. Allicin and cancer hallmarks.Molecules2024296132010.3390/molecules29061320 38542956
    [Google Scholar]
27. ÜnsalN. KoçakD.P. YilmazH. Şahi̇nF. YildirimC.M. The apoptotic effect of garlic (Allium sativum) derived SEVs on different types of cancer cell lines in vitro.Turk. J. Biol.202448318219110.55730/1300‑0152.2694 39050709
    [Google Scholar]