Skip to content
2000
Volume 21, Issue 1
  • ISSN: 1573-4013
  • E-ISSN: 2212-3881

Abstract

In their search for life, space scientists are looking for traces of water on other planets in the solar system because of the well accepted knowledge that water is important for all living systems. Water makes up 60-75% of human body weight. A loss of just 4% of total body water can lead to severe dehydration, and a loss of 15% is fatal. What makes water so essential for survival? Though life on earth is described as a carbon-based phenomenon, it would not be amiss to also call it a water-based phenomenon, as water is the universal solvent that dissolves all biological molecules. Despite this deep understanding of both the chemistry and the biochemical importance of water in human physiology, questions still remain regarding what is the required consumption of water? What type of water is to be ingested? In the context of Nutrition, water is not only an essential nutrient but is also an important source of antinutrients and toxins. Another question that remains ambiguous is: How much water is essential? If it is a nutrient, does it have an RDA? Can one suffer and die from water intoxication? This review puts together in simple terms what one needs to know about water as an essential nutrient in our diet.

Loading

Article metrics loading...

/content/journals/cnf/10.2174/0115734013284543240305103449
2024-03-12
2025-09-27
Loading full text...

Full text loading...

References

  1. ColeridgeS.T. The rime of the ancient mariner.Available from: https://www.poetryfoundation.org/poems/43997/the-rime-of-the-ancient-mariner-text-of-1834
  2. NASA confirms evidence that liquid water flows on today’s mars.Available from: https://www.nasa.gov/press-release/nasa-confirms-evidence-that-liquid-water-flows-on-today-s-mars/
  3. CooperG.M. The cell: A molecular approach.International eighth editionNew York, OxfordSinauer Associates, Oxford University Press2019
    [Google Scholar]
  4. SwyerP.R. Assumptions used in measurements of energy metabolism.J. Nutr.1991121111891189610.1093/jn/121.11.18911941198
    [Google Scholar]
  5. BhallaG. Woman dies of “water intoxication”: Here’s how to keep your water.Available from: https://www.indiatimes.com/news/world/us-woman-dies-of-water-intoxication-611578.html
  6. FershtA.R. The hydrogen bond in molecular recognition.Trends Biochem. Sci.19871230130410.1016/0968‑0004(87)90146‑0
    [Google Scholar]
  7. StillingerF.H. Water revisited.Science1980209445545145710.1126/science.209.4455.45117831355
    [Google Scholar]
  8. FriedenE. Non-covalent interactions: Key to biological flexibility and specificity.J. Chem. Educ.1975521275475610.1021/ed052p754172524
    [Google Scholar]
  9. TegenawA. SorialG.A. Sahle-DemessieE. HanC. Role of water chemistry on stability, aggregation, and dissolution of uncoated and carbon-coated copper nanoparticles.Environ. Res.202018710970010.1016/j.envres.2020.10970032480027
    [Google Scholar]
  10. SahaI. BhattacharyaS. MukhopadhyayA. ChattopadhyayD. GhoshU. ChatterjeeD. Role of nanotechnology in water treatment and purification: Potential applications and implications.Intern. J. Chem. Sci. Techno.2013335964
    [Google Scholar]
  11. ChakravartyP. NagapudiK. The importance of water-solid interactions in small molecule drug development: An industry perspective.Trends Analyt. Chem.202114011627610.1016/j.trac.2021.116276
    [Google Scholar]
  12. Herrera-DomínguezM. Morales-LunaG. MahlknechtJ. ChengQ. Aguilar-HernándezI. Ornelas-SotoN. Optical biosensors and their applications for the detection of water pollutants.Biosensors202313337010.3390/bios1303037036979582
    [Google Scholar]
  13. ChaplinM.F. Water: Its importance to life.Biochem. Mol. Biol. Educ.2001292545910.1111/j.1539‑3429.2001.tb00070.x
    [Google Scholar]
  14. ReichardtK. TimmL.C. Water, the universal solvent for life.Soil, Plant and Atmosphere.ChamSpringer International Publishing202071310.1007/978‑3‑030‑19322‑5_2
    [Google Scholar]
  15. PohorilleA. PrattL.R. Is water the universal solvent for life?Orig. Life Evol. Biosph.201242540540910.1007/s11084‑012‑9301‑623065397
    [Google Scholar]
  16. McElroneA.J. ChoatB. GambettaG.A. BrodersenC.R. Water uptake and transport in vascular plants.Nature Education Knowledge2013456
    [Google Scholar]
  17. EisenbergD.S. KauzmannW. The structure and properties of water.Oxford : New York: Clarendon Press2005129610.1093/acprof:oso/9780198570264.001.0001
    [Google Scholar]
  18. NelsonD.L. CoxM.M. HoskinsA.A. LehningerA.L. Principles of biochemistry.8th edNew York, NYMacmillan International2021
    [Google Scholar]
  19. SargenM. Biological roles of water: Why is water necessary for life.https://sitn.hms.harvard.edu/uncategorized/2019/biological-roles-of-water-why-is-water-necessary-for-life/
  20. LevyY. OnuchicJ.N. Water mediation in protein folding and molecular recognition.Annu. Rev. Biophys. Biomol. Struct.200635138941510.1146/annurev.biophys.35.040405.10213416689642
    [Google Scholar]
  21. ZhangS. IwataK. LachenmannM.J. PengJ.W. LiS. StimsonE.R. LuY. FelixA.M. MaggioJ.E. LeeJ.P. The Alzheimer’s peptide a β adopts a collapsed coil structure in water.J. Struct. Biol.20001302-313014110.1006/jsbi.2000.428810940221
    [Google Scholar]
  22. WangT. JoH. DeGradoW.F. HongM. Water distribution, dynamics, and interactions with alzheimer’s β-amyloid fibrils investigated by solid-state NMR.J. Am. Chem. Soc.2017139176242625210.1021/jacs.7b0208928406028
    [Google Scholar]
  23. SherwoodL. Human physiology: from cells to systems.9th edBoston, MA, USACengage Learning2016
    [Google Scholar]
  24. BrinkmanJ. SharmaS. Physiology, body fluids.2018Available from: https://www.researchgate.net/publication/323497360_Physiology_Body_Fluids
  25. Fluid, electrolyte, and acid-base disorders in small animal practice.2006Available from: https://linkinghub.elsevier.com/retrieve/pii/B0721639496X50012
  26. PopkinB.M. D’AnciK.E. RosenbergI.H. Water, hydration, and health.Nutr. Rev.201068843945810.1111/j.1753‑4887.2010.00304.x20646222
    [Google Scholar]
  27. ShaheenN.A. AlqahtaniA.A. AssiriH. AlkhodairR. HusseinM.A. Public knowledge of dehydration and fluid intake practices: variation by participants’ characteristics.BMC Public Health2018181134610.1186/s12889‑018‑6252‑530518346
    [Google Scholar]
  28. Hassan STF. ManthattilF. Perspective of recent advances in acute diarrhea.Dehydrationintechopen2020
    [Google Scholar]
  29. TaylorK.B. JonesE. Adult dehydration.In: StatPearlsStatPearls Publishing2023
    [Google Scholar]
  30. RieblS.K. DavyB.M. The hydration equation.ACSM’s Health Fit. J.2013176212810.1249/FIT.0b013e3182a9570f25346594
    [Google Scholar]
  31. GrandjeanA.C. Water requirements, impinging factors, and recommended intakes.World Health Organization2004
    [Google Scholar]
  32. MalikD. NarayanasamyN. PratyushaV.A. ThakurJ. SinhaN. Textbook of nutritional biochemistry.Springer2023
    [Google Scholar]
  33. European food safety authority (EFSA)Dietary Reference Values for nutrients Summary report.20171412: e15121E.
    [Google Scholar]
  34. NaharM.S. ZhangJ. Assessment of potable water quality including organic, inorganic, and trace metal concentrations.Environ. Geochem. Health201234114115010.1007/s10653‑011‑9397‑z21670987
    [Google Scholar]
  35. SanduM. MosanuE. GladchiV. TarităA. DucaG. SpataruP. LupascuT. SergentuE. LozanR. JabinV. TurcanS. Study of springs water quality as sources of potable water and for irrigation in rezina district.Chem. J. Mol.201051848910.19261/cjm.2010.05(1).07
    [Google Scholar]
  36. IslamR Assessment of pH and total dissolved substances (TDS) in the commercially available bottled drinking water.IOSR J. Nurs. Health Sci.2017653540
    [Google Scholar]
  37. van LeeuwenF.X.R. Safe drinking water: The toxicologist’s approach.Food Chem. Toxicol.2000381S51S5810.1016/S0278‑6915(99)00140‑410717371
    [Google Scholar]
  38. ZulkifliS.N. RahimH.A. LauW.J. Detection of contaminants in water supply: A review on state-of-the-art monitoring technologies and their applications.Sens. Actuators B Chem.20182552657268910.1016/j.snb.2017.09.07832288249
    [Google Scholar]
  39. ShahA. ArjunanA. BaroutajiA. ZakharovaJ. A review of physicochemical and biological contaminants in drinking water and their impacts on human health.Water Sci. Eng.202316433334410.1016/j.wse.2023.04.003
    [Google Scholar]
  40. BrovaroneA.V. ButchC.J. CiappaA. CleavesH.J.II ElmalehA. FaccendaM. FeinemanM. HermannJ. NestolaF. CordoneA. GiovannelliD. Let there be water: How hydration/dehydration reactions accompany key Earth and life processes.Am. Mineral.202010581152116010.2138/am‑2020‑7380
    [Google Scholar]
  41. KavourasS.A. Hydration, dehydration, underhydration, optimal hydration: are we barking up the wrong tree?Eur. J. Nutr.201958247147310.1007/s00394‑018‑01889‑z30607564
    [Google Scholar]
  42. ThomasD.R. CoteT.R. LawhorneL. LevensonS.A. RubensteinL.Z. SmithD.A. StefanacciR.G. TangalosE.G. MorleyJ.E. Dehydration Council Understanding clinical dehydration and its treatment.J. Am. Med. Dir. Assoc.20089529230110.1016/j.jamda.2008.03.00618519109
    [Google Scholar]
  43. Lavizzo-MoureyR.J. Dehydration in the elderly: A short review.J. Natl. Med. Assoc.19877910103310383316670
    [Google Scholar]
  44. El-SharkawyA.M. SahotaO. LoboD.N. Acute and chronic effects of hydration status on health.Nutr. Rev.2015739710910.1093/nutrit/nuv03826290295
    [Google Scholar]
  45. EdmondsC.J. CrombieR. BallieuxH. GardnerM.R. DawkinsL. Water consumption, not expectancies about water consumption, affects cognitive performance in adults.Appetite201360114815310.1016/j.appet.2012.10.01623104227
    [Google Scholar]
  46. EdmondsC.J. HarteN. GardnerM. How does drinking water affect attention and memory? The effect of mouth rinsing and mouth drying on children’s performance.Physiol. Behav.201819423323810.1016/j.physbeh.2018.06.00429885324
    [Google Scholar]
  47. WestfallD.R. LoganN.E. KhanN.A. HillmanC.H. Cognitive assessments in hydration research involving children: Methods and considerations.Ann. Nutr. Metab.201974192410.1159/00050034131203295
    [Google Scholar]
  48. VieiraG.R. LeôncioL.M.D.L. BezerraC.G. DavidM.C.M.M. MatosR.J.B.D. Is there a functional relationship between hydration and memory in children and adolescents? A meta-analysis.Rev. Cienc. Salud20211128293
    [Google Scholar]
  49. ShimizuM. KinoshitaK. HattoriK. OtaY. KanaiT. KobayashiH. TokudaY. Physical signs of dehydration in the elderly.Intern. Med.201251101207121010.2169/internalmedicine.51.705622687791
    [Google Scholar]
  50. BeckA.M. SeemerJ. KnudsenA.W. MunkT. Narrative review of low-intake dehydration in older adults.Nutrients2021139314210.3390/nu1309314234579019
    [Google Scholar]
  51. EdmondsC.J. FogliaE. BoothP. FuC.H.Y. GardnerM. Dehydration in older people: A systematic review of the effects of dehydration on health outcomes, healthcare costs and cognitive performance.Arch. Gerontol. Geriatr.20219510438010.1016/j.archger.2021.10438033636649
    [Google Scholar]
  52. BegumMN JohnsonCS A review of the literature on dehydration in the institutionalized elderly. e-SPEN.The Euro. J. Clin. Nutr. Metab.2010514753
    [Google Scholar]
  53. DundasB. HarrisM. NarasimhanM. Psychogenic polydipsia review: Etiology, differential, and treatment.Curr. Psychiatry Rep.20079323624110.1007/s11920‑007‑0025‑717521521
    [Google Scholar]
  54. LeeS. ChowC.C. KooL.C.L. Altered state of consciousness in a compulsive water drinker.Br. J. Psychiatry1989154455655810.1192/bjp.154.4.5562590788
    [Google Scholar]
  55. ThompsonC.J. EdwardsC.R.W. BaylisP.H. Osmotic and non-osmotic regulation of thirst and vasopressin secretion in patients with compulsive water drinking.Clin. Endocrinol.199135322122810.1111/j.1365‑2265.1991.tb03526.x1742879
    [Google Scholar]
  56. MarozN. MarozU. IqbalS. AiyerR. KambhampatiG. EjazA.A. Nonobstructive hydronephrosis due to social polydipsia: A case report.J. Med. Case Reports20126137610.1186/1752‑1947‑6‑37623130747
    [Google Scholar]
  57. BlumA. FriedlandG.W. Urinary tract abnormalities due to chronic psychogenic polydipsia.Am. J. Psychiatry1983140791591610.1176/ajp.140.7.9156859314
    [Google Scholar]
  58. HosseiniSM Neuroscience research center, department of physiology, faculty of medicine.World J. Cardiol.2019124144154
    [Google Scholar]
  59. DekkerM.J.E. KoningsC. CanaudB. van der SandeF.M. StuardS. RaimannJ.G. ÖztürkE. UsvyatL. KotankoP. KoomanJ.P. Interactions between malnutrition, inflammation, and fluid overload and their associations with survival in prevalent hemodialysis patients.J. Ren. Nutr.201828643544410.1053/j.jrn.2018.06.00530146272
    [Google Scholar]
  60. LeeL.C. NoronhaM. When plenty is too much: Water intoxication in a patient with a simple urinary tract infection.BMJ Case Rep.20162016bcr201621688210.1136/bcr‑2016‑21688227803013
    [Google Scholar]
  61. DekkerM.J.E. van der SandeF.M. van den BergheF. LeunissenK.M.L. KoomanJ.P. Fluid overload and inflammation axis.Blood Purif.2018451-315916510.1159/00048515329478061
    [Google Scholar]
  62. FarrellD.J. BowerL. Fatal water intoxication.J. Clin. Pathol.20035610803-a80410.1136/jcp.56.10.803‑a14514793
    [Google Scholar]
  63. Hew-ButlerT. Smith-HaleV. Pollard-McGrandyA. VanSumerenM. Of mice and men—the physiology, psychology, and pathology of overhydration.Nutrients2019117153910.3390/nu1107153931284689
    [Google Scholar]
  64. KalraD. Overhydration: A boon or bane.Indian J. Pharma. Pharma.2023102737510.18231/j.ijpp.2023.017
    [Google Scholar]
  65. O’BrienK.K. MontainS.J. CorrW.P. SawkaM.N. KnapikJ.J. CraigS.C. Hyponatremia associated with overhydration in U.S. Army trainees.Mil. Med.2001166540541010.1093/milmed/166.5.40511370203
    [Google Scholar]
  66. ArmstrongL. JohnsonE. Water intake, water balance, and the elusive daily water requirement.Nutrients20181012192810.3390/nu1012192830563134
    [Google Scholar]
  67. VoroneanuL. GavriloviciC. CovicA. Overhydration, underhydration, and total body sodium: A tricky “ménage a trois” in dialysis patients.Semin. Dial.2018311212510.1111/sdi.1264928967233
    [Google Scholar]
  68. StormontJ.M. WaterhouseC. The genesis of hyponatremia associated with marked overhydration and water intoxication.Circulation196124219120310.1161/01.CIR.24.2.191
    [Google Scholar]
/content/journals/cnf/10.2174/0115734013284543240305103449
Loading
/content/journals/cnf/10.2174/0115734013284543240305103449
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test