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Green nanotechnology entails the combination of nanoscience, green chemistry, and sustainable engineering in order to develop safe, energy-saving, and biodegradable drug delivery systems. Green systems, unlike traditional nanomaterials that rely on toxic solvents and high energy inputs, involve the use of plant extracts, natural polymers, and environmentally friendly processes to produce biocompatible nanocarriers. This editorial provides insight into how green nanotechnology can be used to enhance pharmaceutical innovation as a way of solving sustainability, safety, and regulatory issues. It goes on to highlight that the world regulators (FDA, EMA, CDSCO) should develop sustainability-specific guidelines and increase partnership between academia and industry. Green nanotechnology has the ability to transform the face of pharmaceutics to a more patient-centered and environmentally friendly environment by integrating sustainability measures and encouraging collaboration within the industry.