Skip to content
2000
Volume 21, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603

Abstract

Background

Collagenous fibroma (CF), or desmoplastic fibroblastoma, is a rare benign tumor with few reported cases involving the facial region. Its presence in uncommon sites can pose diagnostic challenges due to overlapping clinical and radiologic features with malignant neoplasms.

Case Presentation

Herein, we report a case of a 48-year-old female with CF in the juxtaforaminal premaxillary fat pad, presenting with neuralgic pain extending to the ipsilateral upper gingiva. The patient had a history of adenoid cystic carcinoma (AdCC) of the right nasolabial fold, which was treated surgically four years prior. During evaluation with a multimodal radiologic approach using ultrasonography, CT, and MRI, the lesion was revealed to be a soft tissue lesion in the premaxillary region, raising suspicion of recurrent AdCC. However, histopathologic examination of the surgical excision confirmed the diagnosis of CF.

Conclusion

This case highlights the importance of integrating clinical history, imaging findings, and pathological analysis for accurate diagnosis and appropriate management.

This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
Loading

Article metrics loading...

/content/journals/cmir/10.2174/0115734056391917250730080108
2025-08-04
2025-10-29
Loading full text...

Full text loading...

/deliver/fulltext/cmir/21/1/CMIR-21-E15734056391917.html?itemId=/content/journals/cmir/10.2174/0115734056391917250730080108&mimeType=html&fmt=ahah

References

  1. EvansH.L. Desmoplastic fibroblastoma.Am. J. Surg. Pathol.19951991077108110.1097/00000478‑199509000‑000127661281
    [Google Scholar]
  2. MiettinenM. Soft tissue tumors and their differential diagnosis.Mod. Pathol.200316401426
    [Google Scholar]
  3. WalkerK.R. Bui-MansfieldL.T. GeringS.A. RanlettR.D. Collagenous fibroma (desmoplastic fibroblastoma) of the shoulder.AJR Am. J. Roentgenol.20041836176610.2214/ajr.183.6.0183176615547225
    [Google Scholar]
  4. FletcherC.D.M. BridgeJ.A. HogendoornP.C.W. MertensF. WHO Classification of Tumours of Soft Tissue and Bone.4th edLyonIARC Press2013
    [Google Scholar]
  5. LiuX. GuoX. WangL. ChenY. YuH. SunZ. Unusual appearance of nasal collagenous fibroma (desmoplastic fibroblastoma) on imaging.J. Coll. Physicians Surg. Pak.20223281064106610.29271/jcpsp.2022.08.106435932135
    [Google Scholar]
  6. YamamotoA. AbeS. ImamuraT. TakadaK. EnomotoY. HarasawaA. MatsushitaT. FuruiS. Three cases of collagenous fibroma with rim enhancement on postcontrast T1-weighted images with fat suppression.Skeletal Radiol.201342114114610.1007/s00256‑012‑1484‑422829025
    [Google Scholar]
  7. KresseM.E. KransdorfM.J. FoxM.G. FlugJ.A. LongJ.R. MurpheyM.D. Desmoplastic fibroblastoma: An uncommon tumor with a relatively characteristic MRI appearance.AJR Am. J. Roentgenol.2020215117818310.2214/AJR.19.2216332406775
    [Google Scholar]
  8. MoonJ.C.C. ReedE. SheppardM.N. ElkingtonA.G. HoS. BurkeM. PetrouM. PennellD.J. The histologic basis of late gadolinium enhancement cardiovascular magnetic resonance in hypertrophic cardiomyopathy.J. Am. Coll. Cardiol.200443122260226410.1016/j.jacc.2004.03.03515193690
    [Google Scholar]
  9. FontanaM. PicaS. ReantP. Abdel-GadirA. TreibelT.A. BanypersadS.M. MaestriniV. BarcellaW. RosminiS. BulluckH. SayedR.H. PatelK. MamhoodS. Bucciarelli-DucciC. WhelanC.J. HerreyA.S. LachmannH.J. WechalekarA.D. ManistyC.H. SchelbertE.B. KellmanP. GillmoreJ.D. HawkinsP.N. MoonJ.C. Prognostic value of late gadolinium enhancement cardiovascular magnetic resonance in cardiac amyloidosis.Circulation2015132161570157910.1161/CIRCULATIONAHA.115.01656726362631
    [Google Scholar]
  10. GiuffridaA.Y. KoniarisL.G. GutierrezJ.C. Collagenous fibroma: Clinical and pathologic features.J. Surg. Oncol.200897626631
    [Google Scholar]
  11. NishioJ. AkihoS. IwasakiH. NaitoM. Translocation t(2;11) is characteristic of collagenous fibroma (desmoplastic fibroblastoma).Cancer Genet.20112041056957110.1016/j.cancergen.2011.10.00322137488
    [Google Scholar]
  12. GrewalR. NatterP. MakaryR. SillimanJ. Desmoplastic fibroblastoma of the left upper arm.BMJ Case Rep.20182018bcr-2017-22173810.1136/bcr‑2017‑22173829374633
    [Google Scholar]
  13. ShutoR. KiyosueH. HoriY. MiyakeH. KawanoK. MoriH. CT and MR imaging of desmoplastic fibroblastoma.Eur. Radiol.200212102474247610.1007/s00330‑001‑1217‑x12271387
    [Google Scholar]
  14. YunJ.M. ChangS. SoY.K. Collagenous fibroma at the surgical site after thyroidectomy for papillary thyroid carcinoma.Korean J. Otorhinolaryngol.-Head Neck Surg.2021641293293610.3342/kjorl‑hns.2020.00906
    [Google Scholar]
/content/journals/cmir/10.2174/0115734056391917250730080108
Loading
/content/journals/cmir/10.2174/0115734056391917250730080108
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test