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2000
Volume 21, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603

Abstract

Background

Gastric schwannoma is a rare gastrointestinal mesenchymal tumor with Schwann cell differentiation. In the past, most of the published cases were single gastric schwannoma. Multiple gastric schwannoma is exceedingly rare. We herein report a case of multiple gastric schwannomas.

Case Presentation

A 55-year-old male presented with postprandial vomiting of unclear etiology, accompanied by epigastric pain and bloating. Computed tomography revealed marked thickening of the gastric wall at the fundus-body junction along the greater curvature and gastric angle, with intraluminal nodular projections. Multiphase contrast-enhanced computed tomography demonstrated moderate progressive enhancement. The patient was misdiagnosed as having a gastric stromal tumor before the operation and subsequently underwent laparoscopic partial gastrectomy. However, pathological and immunohistochemical analysis confirmed multiple gastric schwannomas. The patient recovered uneventfully and was discharged without complications.

Conclusion

Gastric schwannoma is rare in clinical practice, especially gastric multiple schwannomas, which are easily confused with gastric stromal tumors, as illustrated in this case, where a preoperative misdiagnosis occurred. Clinicians should enhance their recognition of characteristic imaging features (including Computed tomography, Magnetic resonance imaging, and Positron emission tomography) and employ multimodal diagnostic approaches to optimize preoperative diagnosis.

This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2025-05-15
2025-09-03
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