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2000
Volume 21, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
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Abstract

Introduction

Small cell neuroendocrine carcinoma (SCNEC) of the ureter is extremely rare, and tends to show a mixed histologic profile. Literature on its imaging features is limited.

Case Presentation

We herein report the case of a 68-year-old woman who presented with two days of left flank pain. Ultrasound and CT scan revealed a lesion in the left distal ureter. The lesion exhibited intensive tracer activity on 18F-FDG PET/CT scan, corresponding to a malignant tumor, most likely a high-grade urothelial carcinoma, and no metastases were observed. Then, the patient underwent a radical left nephroureterectomy. Pathology revealed a carcinoma composed of SCNEC (approximately 83%) and urothelial carcinoma (approximately 17%). During one year of follow-up, the patient underwent six cycles of adjuvant chemotherapy (etoposide 100mg d1-3 + cisplatin 30mg d1-3, q3w), and no recurrence or metastases were found on the CT scan.

Conclusion

This case report has presented a case of ureteral SCNEC and explored the value of 18F-FDG PET/CT in the diagnosis and staging of the disease.

© The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2025-05-13
2025-09-02

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Small Cell Neuroendocrine Carcinoma of the Ureter: A Case Evaluated by 18F-FDG-PET/CT and Literature Review
Curr. Med. Imaging 21, E15734056353458 (2025); https://doi.org/10.2174/0115734056353458250429063852
/content/journals/cmir/10.2174/0115734056353458250429063852
/content/journals/cmir/10.2174/0115734056353458250429063852
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  • Article Type:     Case Report
Keyword(s): Chemotherapy; Intensive tracer activity; PET/CT; small cell neuroendocrine carcinoma; ureter

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