Skip to content
2000
Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
file format pdf download PDF
side by side viewer icon HTML

Abstract

Background

Fetal small bowel obstruction (SBO) is a serious condition with high morbidity and mortality rates. Prenatal ultrasound is an important tool for detecting SBO, but the optimal cutoff value for intestinal diameter remains undefined.

Objective

This study aimed to investigate the ultrasonic characteristics of fetal SBO and determine the optimal cutoff value for intestinal diameter to enhance prenatal ultrasound diagnosis.

Methods

We retrospectively analyzed the ultrasonic characteristics and postpartum data of 76 cases diagnosed with SBO. Receiver operating characteristic (ROC) curve analysis was performed to identify the optimal cutoff value for dilated intestinal diameter.

Results

Among the 76 cases, 31 displayed the “double bubble sign” on ultrasound, with 20 cases identified as annular pancreas, 6 as duodenal atresia, and 5 as duodenal membranous stenosis. In 45 cases, the lesions were located in the jejunal or ileal segment and exhibited intestinal dilatation above the lesion site, including 27 cases of small bowel atresia, 7 cases of membranous jejunal stenosis, and 11 cases of small bowel volvulus. Out of the 76 cases, 9 showed no abnormalities after birth. ROC curve analysis determined optimal cutoff values of 17.5mm and 10.5mm for predicting “double bubble sign” lesions in the gastric and duodenal widths. For predicting small intestinal dilatation, the optimal cutoff values for dilated width and length of the intestinal tube were 11.5mm and 21.5mm, respectively, with high sensitivity and specificity.

Conclusion

Ultrasonic imaging and changes in intestinal diameter provide valuable information for prenatal diagnosis and management of SBO. Establishing these cutoff values can improve the accuracy of prenatal ultrasound diagnosis for SBO.

© 2023 Samman and Bahanan
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Loading

Article metrics loading...

/content/journals/cmir/10.2174/0115734056262425231031171130
2023-01-01
2025-08-16

  • From This Site

    /content/journals/cmir/10.2174/0115734056262425231031171130
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
The full text of this item is not currently available.

References

  1. LiuJ. ChenY. WangH. HuangD. DuY. LiuX. SunX. YanC. ChenW. WangH. ZhangR. Novel qualitative and quantitative ultrasound markers to facilitate prenatal diagnosis of congenital duodenal obstruction.J. Matern. Fetal Neonatal Med.2023361216707210.1080/14767058.2023.216707236726301
     [Google Scholar]
  2. Didier-MathonH. GréventD. Khen-DunlopN. SonigoP. RousseauV. VilleY. BoddaertN. KermorvantE. MahallatiH. SalomonL.J. MillischerA.É. Ultrasound and Fetal MRI Complementary Contributions to Appropriate Counseling in Small Bowel Obstruction.Fetal Diagn. Ther.202148856757410.1159/00051772834461616
     [Google Scholar]
  3. LupoP.J. IsenburgJ.L. SalemiJ.L. MaiC.T. LibermanR.F. CanfieldM.A. CopelandG. HaightS. HarpavatS. HoytA.T. MooreC.A. NembhardW.N. NguyenH.N. RutkowskiR.E. SteeleA. AlversonC.J. StallingsE.B. KirbyR.S. Population-based birth defects data in the United States, 2010-2014: A focus on gastrointestinal defects.Birth Defects Res.2017109181504151410.1002/bdr2.114529152924
     [Google Scholar]
  4. LiX. ZhaoZ. LiX. ZhaoM. KefeiH. Appearance of fetal intestinal obstruction on fetal MRI.Prenat. Diagn.202040111398140710.1002/pd.577932594545
     [Google Scholar]
  5. KilbrideH. CastorC. AndrewsW. Congenital duodenal obstruction: Timing of diagnosis during the newborn period.J. Perinatol.201030319720010.1038/jp.2009.14319798044
     [Google Scholar]
  6. BurjonrappaS. CreteE. BouchardS. Comparative outcomes in intestinal atresia: A clinical outcome and pathophysiology analysis.Pediatr. Surg. Int.201127443744210.1007/s00383‑010‑2729‑820820789
     [Google Scholar]
  7. BishopJ.C. McCormickB. JohnsonC.T. MillerJ. JelinE. BlakemoreK. JelinA.C. The Double Bubble Sign: Duodenal Atresia and Associated Genetic Etiologies.Fetal Diagn. Ther.20204729810310.1159/00050047131167209
     [Google Scholar]
  8. DemirciO. Eriç ÖzdemirM. KumruP. CelayirA. Clinical significance of prenatal double bubble sign on perinatal outcome and literature review.J. Matern. Fetal Neonatal Med.202235101841184710.1080/14767058.2021.187433833455511
     [Google Scholar]
  9. NybergD.A. MackL.A. PattenR.M. CyrD.R. Fetal bowel. Normal sonographic findings.J. Ultrasound Med.1987613610.7863/jum.1987.6.1.33546721
     [Google Scholar]
  10. YoudenW.J. Index for rating diagnostic tests.Cancer195031323510.1002/1097‑0142(1950)3:1<32::AID‑CNCR2820030106>3.0.CO;2‑315405679
     [Google Scholar]
  11. AnnaB. Fetal and prenatal implications of anomalies in the gastrointestinal tract and the abdominal wall.TrondheimNorwegian University of Science and Technology2007
     [Google Scholar]
  12. LawrenceM.J. FordW.D.A. FurnessM.E. HaywardT. WilsonT. Congenital duodenal obstruction: Early antenatal ultrasound diagnosis.Pediatr. Surg. Int.2000165-634234510.1007/s00383990032210955559
     [Google Scholar]
  13. DankovcikR. JirasekJ.E. KuceraE. FeyereislJ. RadonakJ. DudasM. Prenatal diagnosis of annular pancreas: Reliability of the double bubble sign with periduodenal hyperechogenic band.Fetal Diagn. Ther.200824448349010.1159/00017875919047797
     [Google Scholar]
  14. ShawisR. AntaoB. Prenatal bowel dilatation and the subsequent postnatal management.Early Hum. Dev.200682529730310.1016/j.earlhumdev.2006.02.00516626900
     [Google Scholar]
  15. YangY. HeP. LiD.Z. Clinical outcome of pregnancies with the prenatal double bubble sign – a five-year experience from one single centre in mainland China.J. Obstet. Gynaecol.201838220620910.1080/01443615.2017.134223028880692
     [Google Scholar]
  16. VolpeP. PaladiniD. Ultrasound of Congenital Fetal Anomalies.LondonInforma UK Ltd2014
     [Google Scholar]
  17. FeldmanN. MelcerY. Levinsohn-TavorO. OrensteinA. SvirskyR. HermanA. MaymonR. Prenatal ultrasound charts of orbital total axial length measurement (TAL): A valuable data for correct fetal eye malformation assessment.Prenat. Diagn.201535655856310.1002/pd.457225655829
     [Google Scholar]
  18. EkwunifeO.H. OguejioforI.C. ModekweV.I. OsuigweA.N. Jejuno-ileal atresia: A 2-year preliminary study on presentation and outcome.Niger. J. Clin. Pract.201215335435710.4103/1119‑3077.10064722960975
     [Google Scholar]
  19. ArbellD. KoplewitzB.Z. PintoM. NadjariM. Prepartum sonographic demonstration of ‘to-and-fro’ motion in fetal intestinal obstruction: A novel sign for immediate postnatal surgery.Ultrasound Obstet. Gynecol.200832111211410.1002/uog.530418435527
     [Google Scholar]
  20. BartholmotC. FaureJ.M. GrosjeanF. CoutureA. ForguesD. FuchsF. ProdhommeO. Prenatal diagnosis of antenatal midgut volvulus: Specific ultrasound features.Prenat. Diagn.2019391162510.1002/pd.539230536936
     [Google Scholar]
  21. SciarroneA. TeruzziE. PertusioA. BastoneroS. ErranteG. TodrosT. VioraE. Fetal midgut volvulus: Report of eight cases.J. Matern. Fetal Neonatal Med.20162981322132710.3109/14767058.2015.104733626103780
     [Google Scholar]
  22. ChakrabortyA. AyoobA. DiSantisD. Coffee bean sign.Abdom. Imaging20154072904290510.1007/s00261‑015‑0402‑325787246
     [Google Scholar]
  23. JakhereS.G. SaifiS.A. RanwakaA.A. Fetal small bowel volvulus without malrotation: The whirlpool & coffee bean signs.J. Neonatal Perinatal Med.20147214314610.3233/NPM‑147601325104121
     [Google Scholar]
/content/journals/cmir/10.2174/0115734056262425231031171130
Loading
Prenatal Ultrasound Diagnosis and Clinical Analysis of Fetal Small Bowel Obstruction
Curr. Med. Imaging 20, e15734056262425 (2024); https://doi.org/10.2174/0115734056262425231031171130
/content/journals/cmir/10.2174/0115734056262425231031171130
/content/journals/cmir/10.2174/0115734056262425231031171130
Loading

Data & Media loading...


  • Article Type:     Research Article
Keyword(s): AP; Digestive tract; Fetus; Intestinal diameter; Prenatal ultrasound examination; Small bowel obstruction (SBO)

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test