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2000
Volume 33, Issue 6
  • ISSN: 0929-8673
  • E-ISSN: 1875-533X

Abstract

Aim

Early and precise diagnosis is essential for effectively treating and managing pulmonary tuberculosis. The purpose of this research is to leverage artificial intelligence (AI), specifically convolutional neural networks (CNNs), to expedite the diagnosis of tuberculosis (TB) using chest X-ray (CXR) images.

Background

, an aerobic bacterium, is the causative agent of TB. The disease remains a global health challenge, particularly in densely populated countries. Early detection chest X-rays is crucial, but limited medical expertise hampers timely diagnosis.

Objective

This study explores the application of CNNs, a highly efficient method, for automated TB detection, especially in areas with limited medical expertise.

Methods

Previously trained models, specifically VGG-16, VGG-19, ResNet 50, and Inception v3, were used to validate the data. Effective feature extraction and classification in medical image analysis, especially in TB diagnosis, is facilitated by the distinct design and capabilities that each model offers. VGG-16 and VGG-19 are very good at identifying minute distinctions and hierarchical characteristics from CXR images; on the other hand, ResNet 50 avoids overfitting while retaining both low and high-level features. The inception v3 model is quite useful for examining various complex patterns in a CXR image with its capacity to extract multi-scale features.

Results

Inception v3 outperformed other models, attaining 97.60% accuracy without pre-processing and 98.78% with pre-processing.

Conclusion

The proposed model shows promising results as a tool for improving TB diagnosis, and reducing the global impact of the disease, but further validation with larger and more diverse datasets is needed.

© 2026 Bentham Science Publishers
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Transfer Learning for Automated Two-class Classification of Pulmonary Tuberculosis in Chest X-Ray Images
Curr. Med. Chem. 33, 1264 (2026); https://doi.org/10.2174/0109298673375085250704061619
/content/journals/cmc/10.2174/0109298673375085250704061619
/content/journals/cmc/10.2174/0109298673375085250704061619
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  • Article Type:     Research Article
Keyword(s): artificial intelligence; chest X-ray images; convolutional neural network; deep learning; Mycobacterium tuberculosis; TB diagnosis; tuberculosis

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