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2000
Volume 2, Issue 1
  • ISSN: 2666-8629
  • E-ISSN: 2666-8637

Abstract

The medicinal plants discussed at this moment and their active isolated components seem promising for the treatment of neurodegenerative diseases . Disease (HD) in Huntington, Alzheimer's disease (AD), and Parkinson's disease (PD). These compounds can lay the groundwork for a new pharmacological approach to treatment, as patients tolerate herbal compounds more easily because they are relatively more protective than synthetic drugs. Meanwhile, there are anti-inflammatory, antioxidant, altered tau phosphorylation, anti-amyloidogenic, decreased aggregation of neurofibrillary tangles, and anticholinesterase processes in natural compound structures, including flavonoids, polyphenols, triterpenes, tannins, alkaloids and so on. We have summarized the pathogenesis and mechanism of different natural/bioactive components for treating HD, AD, and PD. An herbal source with well-established antioxidant and neuroprotective activity showed favourable impacts in both and studies against the symptoms of neurodegenerative diseases. The future outlook of herbal medicine can allow us to research their synergistic interactions, the action of multiple targets, and the elucidation of complex mechanisms of neuroprotective properties. However, in future scientific research on bioactive compounds, the efficacy of their active ingredients should be investigated to discover their neuroprotective therapeutic potential. Also, the mechanisms of action of herbal extracts and active ingredients remain to be clarified appropriately.

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2024-04-01
2025-12-07

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/content/journals/cff/10.2174/2666862901666230627124045
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Natural Medicinal Compounds Used in Neurodegenerative Diseases
Curr Func Foods 2, e270623218322 (2024); https://doi.org/10.2174/2666862901666230627124045
/content/journals/cff/10.2174/2666862901666230627124045
/content/journals/cff/10.2174/2666862901666230627124045
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  • Article Type:     Review Article
Keyword(s): Alzheimer's disease; antioxidants; huntington’s disease; neurodegenerative disorders; neuroprotective agents; parkinson’s disease

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